Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 1788414..1789075 Replicon plasmid pmega
Accession NZ_CP115947
Organism Ralstonia solanacearum MolK2

Toxin (Protein)


Gene name vapC Uniprot ID A0A399W071
Locus tag PG909_RS22055 Protein ID WP_003278076.1
Coordinates 1788662..1789075 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PG909_RS22050 Protein ID WP_003278075.1
Coordinates 1788414..1788665 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG909_RS22040 1783838..1784233 - 396 WP_042550185.1 hypothetical protein -
PG909_RS22045 1784239..1788339 - 4101 WP_042550184.1 tape measure protein -
PG909_RS22050 1788414..1788665 + 252 WP_003278075.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PG909_RS22055 1788662..1789075 + 414 WP_003278076.1 type II toxin-antitoxin system VapC family toxin Toxin
PG909_RS22060 1789122..1790219 - 1098 WP_049279767.1 DNA cytosine methyltransferase -
PG909_RS22065 1790753..1791043 + 291 WP_003278079.1 H-NS histone family protein -
PG909_RS22070 1791086..1791730 - 645 WP_003278081.1 DUF6441 family protein -
PG909_RS22075 1791705..1791896 - 192 WP_230675536.1 hypothetical protein -
PG909_RS22080 1791923..1792315 - 393 WP_003278083.1 hypothetical protein -
PG909_RS22085 1792324..1793097 - 774 WP_003278085.1 hypothetical protein -
PG909_RS22090 1793209..1793655 - 447 WP_003278086.1 hypothetical protein -
PG909_RS22095 1793661..1793963 - 303 WP_003278088.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheY / icl 1..2326525 2326525


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-63)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15756.12 Da        Isoelectric Point: 6.2337

>T267532 WP_003278076.1 NZ_CP115947:1788662-1789075 [Ralstonia solanacearum MolK2]
MSYLIDTNVLSELRRKQPDARVLAWMQDRPRQSLYLSVLTLGEIRKGIERLDDAARRQHLIDWLETELPNYFLGRLLDID
AHTADRWGRLMSSANRPLPAIDGLLAATALQHDLILVTRNTKDFVGLDVPLINPWET

Download         Length: 414 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9242.46 Da        Isoelectric Point: 5.0774

>AT267532 WP_003278075.1 NZ_CP115947:1788414-1788665 [Ralstonia solanacearum MolK2]
MQSWQLQAAKARFSDVVKRAADDGPQEITVHGRPVAVVISRALFDRLSGGGESLVDFMRQSPLAGLDDVVFERERSLPRE
VEF

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A399W071

Antitoxin

Source ID Structure

References