267526

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1705936..1707665 Replicon plasmid pmega
Accession NZ_CP115945
Organism Ralstonia syzygii R24

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag PG906_RS24925 Protein ID WP_197334187.1
Coordinates 1705936..1706583 (+) Length 216 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag PG906_RS24930 Protein ID WP_197334186.1
Coordinates 1706580..1707665 (+) Length 362 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG906_RS24905 1701719..1702636 + 918 WP_197334190.1 NAD(P)-dependent oxidoreductase -
PG906_RS24910 1702680..1703720 - 1041 WP_013210739.1 LacI family DNA-binding transcriptional regulator -
PG906_RS24915 1703821..1704714 - 894 WP_197334189.1 DMT family transporter -
PG906_RS24920 1704812..1705618 + 807 WP_197334188.1 helix-turn-helix transcriptional regulator -
PG906_RS24925 1705936..1706583 + 648 WP_197334187.1 DUF4433 domain-containing protein Toxin
PG906_RS24930 1706580..1707665 + 1086 WP_197334186.1 macro domain-containing protein Antitoxin
PG906_RS24935 1708167..1708871 - 705 WP_197334185.1 SDR family oxidoreductase -
PG906_RS24940 1708932..1709354 - 423 WP_048817145.1 MarR family winged helix-turn-helix transcriptional regulator -
PG906_RS24945 1709382..1709783 + 402 WP_275795117.1 hypothetical protein -
PG906_RS24950 1709780..1710046 + 267 WP_197334184.1 hypothetical protein -
PG906_RS24955 1710060..1711682 + 1623 WP_197334183.1 PepSY domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheY / cyaB / flgC / flgG / fliM / fliG / fliI / adeG / cheY / cheB / cheW / motA 1..1751279 1751279


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(15-214)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 216 a.a.        Molecular weight: 25084.63 Da        Isoelectric Point: 7.0391

>T267526 WP_197334187.1 NZ_CP115945:1705936-1706583 [Ralstonia syzygii R24]
MANYQRLNAENAYIWRIVHRQNIPWILDHGLVCANSERLDPNFVPIGNADLIDRRAHRVVPIAPGGTLSDYVPFYFTPFS
PMMYNIYTGRTVRQQRNEDICMLVSTLPVLRQLGIPFVFTDRHAYTQLARFFSDLGDLDQVDWPLLQARNFKRNPDDPEQ
IERYQAETLVHRHLPVTGLTAIVCYNEEVKRELEQLAAARRLNVTVQALPNWYFQ

Download         Length: 648 bp

Antitoxin


Download         Length: 362 a.a.        Molecular weight: 40691.87 Da        Isoelectric Point: 7.0357

>AT267526 WP_197334186.1 NZ_CP115945:1706580-1707665 [Ralstonia syzygii R24]
MITYTQGNLLDAPAEALVNTVNTVGVMGKGIALMFKEKFPENFREYVAACKEGRVQTGKMFVTERMALIGPKWIVNFPTK
QHWRSPSRLEWIVDGLKELRHFIEREHVRSIAIPPLGAGNGSLDWPLVKAAIDAALGDLGGTEVFVYEPTAKYQNVAKRE
GVEKLTPARALIAELVRRYWILGMDCSLLEIQKLAWFLERVIERTDAPNPLQLKFVAHTYGPYANRLDHLLNNLDGSYLH
CDKRIADAGPLDVIWFDDRRSDMLAAYLKSGEMKPYLRALEETTSLIDGFESPFGLELLASLDWLLAREGRDPSVESIRV
GLSEWPGGESAGRRKYRLFDERAIRIGLNRLTERTGVSTCA

Download         Length: 1086 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References