Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 69712..70322 Replicon plasmid pmega
Accession NZ_CP115945
Organism Ralstonia syzygii R24

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PG906_RS18085 Protein ID WP_197334114.1
Coordinates 70014..70322 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PG906_RS18080 Protein ID WP_197328656.1
Coordinates 69712..70017 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG906_RS18070 66974..68119 + 1146 WP_197334116.1 DUF2220 family protein -
PG906_RS18075 68188..69501 - 1314 WP_197334115.1 MFS family transporter -
PG906_RS18080 69712..70017 - 306 WP_197328656.1 putative addiction module antidote protein Antitoxin
PG906_RS18085 70014..70322 - 309 WP_197334114.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PG906_RS18090 70407..70997 - 591 WP_197334113.1 MFS transporter -
PG906_RS18095 71125..71940 - 816 WP_075465905.1 GntR family transcriptional regulator -
PG906_RS18100 72114..72611 - 498 WP_197334452.1 helix-turn-helix domain-containing protein -
PG906_RS18105 72800..73396 + 597 WP_197328660.1 GNAT family N-acetyltransferase -
PG906_RS18110 73652..74086 + 435 WP_197328661.1 VOC family protein -
PG906_RS18115 74356..75237 + 882 WP_197328662.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheY / cyaB / flgC / flgG / fliM / fliG / fliI / adeG / cheY / cheB / cheW / motA 1..1751279 1751279


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-85)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11793.57 Da        Isoelectric Point: 8.5237

>T267523 WP_197334114.1 NZ_CP115945:c70322-70014 [Ralstonia syzygii R24]
MLTIRTTEIFDDWFCSLRDKAAQRRVQVRIDRLQMGNPGDVKAVREGIREMRIDHGPGYRVYFAQRGVILIVLLCGGDKS
TQEADVRRAIDLSRRLDVDNME

Download         Length: 309 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10990.63 Da        Isoelectric Point: 6.4780

>AT267523 WP_197328656.1 NZ_CP115945:c70017-69712 [Ralstonia syzygii R24]
MMMAQHTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARARGMTQIARETGMTREGLYKALSEDGNP
SFATVLKVIRALGIRLHAVPA

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References