Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 3453110..3453771 Replicon chromosome
Accession NZ_CP115944
Organism Ralstonia syzygii R24

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PG906_RS16575 Protein ID WP_197333267.1
Coordinates 3453358..3453771 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID Q8Y121
Locus tag PG906_RS16570 Protein ID WP_011000825.1
Coordinates 3453110..3453361 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG906_RS16560 3448529..3448924 - 396 WP_197333269.1 hypothetical protein -
PG906_RS16565 3448930..3453030 - 4101 WP_197333268.1 tape measure protein -
PG906_RS16570 3453110..3453361 + 252 WP_011000825.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PG906_RS16575 3453358..3453771 + 414 WP_197333267.1 type II toxin-antitoxin system VapC family toxin Toxin
PG906_RS16580 3454430..3455086 + 657 WP_269436999.1 XopAF/AvrXv3 family type III secretion system effector -
PG906_RS16585 3455209..3455853 - 645 WP_197333265.1 DUF6441 family protein -
PG906_RS16590 3455828..3456049 - 222 WP_197333264.1 hypothetical protein -
PG906_RS16595 3456046..3456435 - 390 WP_197333263.1 hypothetical protein -
PG906_RS16600 3456444..3457217 - 774 WP_197333262.1 hypothetical protein -
PG906_RS16605 3457340..3457786 - 447 WP_197333261.1 hypothetical protein -
PG906_RS16610 3457792..3458094 - 303 WP_197333260.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3425083..3488330 63247


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-120)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15603.96 Da        Isoelectric Point: 5.7498

>T267522 WP_197333267.1 NZ_CP115944:3453358-3453771 [Ralstonia syzygii R24]
MSYLIDTNVLSELRRKAPDARVVAWMQDRPRQSLYLSVLTLGEIRKGIERLDDAVRRQNLIDWLEVELPNYFLGRLLDID
AHTADRWGRLMSSAGRPLPAIDGLLAATALQHDLTLVTRNIKDFAGLDVQLINPWEA

Download         Length: 414 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9335.52 Da        Isoelectric Point: 5.0774

>AT267522 WP_011000825.1 NZ_CP115944:3453110-3453361 [Ralstonia syzygii R24]
MQSWQMQAAKARFSDVVKRAADDGPQEITVHGRPVAVVISRALFDRLSGSGESLVSFMRQSPLADQDDVVFERERSLPRE
VEF

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB Q8Y121

References