267521

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2975824..2976377 Replicon chromosome
Accession NZ_CP115944
Organism Ralstonia syzygii R24

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PG906_RS14355 Protein ID WP_197333438.1
Coordinates 2975824..2976117 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID G3A1N4
Locus tag PG906_RS14360 Protein ID WP_071089703.1
Coordinates 2976105..2976377 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG906_RS14325 2971568..2972980 + 1413 WP_197333440.1 hypothetical protein -
PG906_RS14330 2973065..2973568 + 504 WP_197333439.1 hypothetical protein -
PG906_RS14335 2973629..2974666 - 1038 WP_197334913.1 IS481 family transposase -
PG906_RS14340 2974835..2975089 - 255 WP_143012699.1 hypothetical protein -
PG906_RS14345 2975157..2975507 - 351 WP_231649637.1 hypothetical protein -
PG906_RS14350 2975504..2975821 - 318 WP_275793981.1 hypothetical protein -
PG906_RS14355 2975824..2976117 - 294 WP_197333438.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PG906_RS14360 2976105..2976377 - 273 WP_071089703.1 CopG family ribbon-helix-helix protein Antitoxin
PG906_RS14365 2976507..2976806 - 300 WP_197333437.1 hypothetical protein -
PG906_RS14370 2976919..2978592 - 1674 WP_275793984.1 relaxase/mobilization nuclease domain-containing protein -
PG906_RS14375 2978589..2978897 - 309 WP_247570175.1 MobB mobilization protein -
PG906_RS14380 2979196..2979483 + 288 WP_197333434.1 hypothetical protein -
PG906_RS14385 2979573..2979989 + 417 WP_197333433.1 hypothetical protein -
PG906_RS14390 2980297..2980914 + 618 WP_197333432.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2973629..2984746 11117
- flank IS/Tn - - 2973629..2974666 1037


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10866.32 Da        Isoelectric Point: 7.2770

>T267521 WP_197333438.1 NZ_CP115944:c2976117-2975824 [Ralstonia syzygii R24]
VPRVIITEGAAQGLERCRRFLAGKSPEATRRAGQTIARHLATLETTPTIGRPFAELPEWRELVIEFGDSGYVALYRHEPA
DDAVYVLAFRHQKEAGY

Download         Length: 294 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10591.82 Da        Isoelectric Point: 5.5620

>AT267521 WP_071089703.1 NZ_CP115944:c2976377-2976105 [Ralstonia syzygii R24]
MATSLKIDDELKARVQHLASLRDRSPHWIMREAIKLYVEREEARESFKQEALASWTAYQETGRHLTGQEVRTWLETWGTD
HETGLPECHE

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB G3A1N4

References