267520

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 1450681..1451378 Replicon chromosome
Accession NZ_CP115944
Organism Ralstonia syzygii R24

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag PG906_RS07145 Protein ID WP_197334584.1
Coordinates 1450681..1451034 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag PG906_RS07150 Protein ID WP_197334585.1
Coordinates 1451037..1451378 (+) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG906_RS07120 1447214..1447435 + 222 WP_197334579.1 hypothetical protein -
PG906_RS07125 1447532..1447825 - 294 WP_197334580.1 hypothetical protein -
PG906_RS07130 1447892..1449208 + 1317 WP_197334581.1 hypothetical protein -
PG906_RS07135 1449205..1449780 + 576 WP_275794652.1 hypothetical protein -
PG906_RS07140 1450068..1450622 + 555 WP_197334583.1 tyrosine-type recombinase/integrase -
PG906_RS07145 1450681..1451034 + 354 WP_197334584.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PG906_RS07150 1451037..1451378 + 342 WP_197334585.1 helix-turn-helix transcriptional regulator Antitoxin
PG906_RS07155 1451385..1452041 + 657 WP_197334586.1 hypothetical protein -
PG906_RS07160 1452074..1453039 - 966 WP_197334587.1 hypothetical protein -
PG906_RS07165 1453181..1453774 + 594 WP_197334588.1 2OG-Fe(II) oxygenase -
PG906_RS07170 1453848..1454039 - 192 WP_197334589.1 hypothetical protein -
PG906_RS07175 1454053..1456296 - 2244 WP_197334590.1 YcaO-like family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1440416..1457453 17037


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-108)

Antitoxin

Cro/C1-type helix-turn-helix domain

(38-94)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 12916.93 Da        Isoelectric Point: 9.6256

>T267520 WP_197334584.1 NZ_CP115944:1450681-1451034 [Ralstonia syzygii R24]
MPMIRPLRWVGSAKKDLSVMPDDVQDTFGYALHLAQVGGKHSQAKPLKGYGGAGVLEVVEDHQGNTYRAVYTVRYAGAVY
VLHCFQKKSTHGIATPRPDLDLIEARLKAVIALEKER

Download         Length: 354 bp

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12453.50 Da        Isoelectric Point: 9.1041

>AT267520 WP_197334585.1 NZ_CP115944:1451037-1451378 [Ralstonia syzygii R24]
MNTFATIDDIVIEEGSTNPYADLGRPDADEMLVKAGLAHEIAQIIKSRHLTQQRAAELLGMPQPKLSELLRGKFRGISQA
KMIECLNRLGRDVDIVVKKAGRRALGHTHVVVV

Download         Length: 342 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References