Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 66437..67047 Replicon plasmid pmega
Accession NZ_CP115942
Organism Ralstonia syzygii strain BDBR229

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PG904_RS17050 Protein ID WP_078223783.1
Coordinates 66739..67047 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PG904_RS17045 Protein ID WP_013209163.1
Coordinates 66437..66742 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG904_RS17020 61619..62941 + 1323 WP_078221935.1 IS5 family transposase -
PG904_RS17025 63168..63452 - 285 WP_078223782.1 hypothetical protein -
PG904_RS17030 63786..63973 + 188 Protein_54 transposase -
PG904_RS17035 64113..64808 + 696 WP_237331745.1 hypothetical protein -
PG904_RS17040 64913..66226 - 1314 WP_013209162.1 MFS family transporter -
PG904_RS17045 66437..66742 - 306 WP_013209163.1 putative addiction module antidote protein Antitoxin
PG904_RS17050 66739..67047 - 309 WP_078223783.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PG904_RS17055 67132..68331 - 1200 WP_013209165.1 MFS transporter -
PG904_RS17060 68459..69274 - 816 WP_013209166.1 GntR family transcriptional regulator -
PG904_RS17065 69448..69999 - 552 WP_078223784.1 helix-turn-helix domain-containing protein -
PG904_RS17070 70181..70726 + 546 WP_275760125.1 GNAT family N-acetyltransferase -
PG904_RS17075 70983..71417 + 435 WP_013209169.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheY / cheY / cheB / cheW / motA / katA / acrB 1..1578131 1578131
- flank IS/Tn - - 61619..62941 1322


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11821.56 Da        Isoelectric Point: 9.0017

>T267518 WP_078223783.1 NZ_CP115942:c67047-66739 [Ralstonia syzygii]
MLTIRTTEIFDDWFYSLRDKAAQRRVQVRIDRLQMGNPGDVKTVREGIREMRIDHGPGYRVYVAQRGVVLIVLLCGGDKS
TQEADVRRAIDLSRRLDVDNME

Download         Length: 309 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11009.67 Da        Isoelectric Point: 6.7174

>AT267518 WP_013209163.1 NZ_CP115942:c66742-66437 [Ralstonia syzygii]
MMMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARARGMTQIARETGMTREGLYKALSEDGNP
SFATVLKVIRALGIRLHAVPA

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References