Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1767237..1767777 Replicon chromosome
Accession NZ_CP115941
Organism Ralstonia syzygii strain BDBR229

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PG904_RS08410 Protein ID WP_048817440.1
Coordinates 1767517..1767777 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PG904_RS08405 Protein ID WP_078221722.1
Coordinates 1767237..1767524 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG904_RS08385 1762975..1763892 - 918 WP_078221725.1 MurR/RpiR family transcriptional regulator -
PG904_RS08390 1764059..1765348 + 1290 WP_078221724.1 FAD-dependent oxidoreductase -
PG904_RS08395 1765345..1766382 + 1038 WP_078221723.1 xylose isomerase -
PG904_RS08400 1766379..1767224 + 846 WP_013212795.1 TIM barrel protein -
PG904_RS08405 1767237..1767524 - 288 WP_078221722.1 putative addiction module antidote protein Antitoxin
PG904_RS08410 1767517..1767777 - 261 WP_048817440.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PG904_RS08415 1767904..1768215 - 312 WP_048817439.1 Rieske 2Fe-2S domain-containing protein -
PG904_RS08420 1768181..1769329 - 1149 WP_078221721.1 fatty acid desaturase family protein -
PG904_RS08425 1769465..1770517 + 1053 WP_078221720.1 LacI family DNA-binding transcriptional regulator -
PG904_RS08430 1770727..1771644 + 918 WP_075464683.1 sugar ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-79)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9435.79 Da        Isoelectric Point: 10.3136

>T267515 WP_048817440.1 NZ_CP115941:c1767777-1767517 [Ralstonia syzygii]
MRDKRAKARIAARLVSASFGNFGDCKPVGEGVSEMRIDVGAGYRVYYTRQGTVVYILLTGGNKATQAQDIKQAIRMARDL
KESGHD

Download         Length: 261 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 9969.40 Da        Isoelectric Point: 4.5183

>AT267515 WP_078221722.1 NZ_CP115941:c1767524-1767237 [Ralstonia syzygii]
MTETYAPFDAAAYLDSEETIAEFLAAAMEDPNPDVFLAALGAVARACGIAKVAADAGLGRESLYKAISPGAHPRYETIQK
IMRALGVRLNVTPAA

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References