Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1910636..1910781 Replicon chromosome
Accession NZ_CP115930
Organism Klebsiella pneumoniae subsp. pneumoniae strain 43UC01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1910672..1910774 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1910636..1910781 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DLD89_RS09350 (DLD89_09350) 1905766..1907826 + 2061 WP_032422099.1 oligopeptidase B -
DLD89_RS09355 (DLD89_09355) 1907830..1908489 - 660 WP_002911407.1 exodeoxyribonuclease X -
DLD89_RS09360 (DLD89_09360) 1908568..1908798 - 231 WP_002911406.1 DNA polymerase III subunit theta -
DLD89_RS09365 (DLD89_09365) 1908911..1909285 + 375 WP_004151448.1 CopC domain-containing protein YobA -
DLD89_RS09370 (DLD89_09370) 1909289..1910158 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
DLD89_RS09375 (DLD89_09375) 1910175..1910513 + 339 WP_002911404.1 YebY family protein -
- 1910636..1910781 - 146 - - Antitoxin
- 1910672..1910774 + 103 - - Toxin
DLD89_RS09380 (DLD89_09380) 1911149..1911292 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
DLD89_RS09385 (DLD89_09385) 1911397..1912365 - 969 WP_004151446.1 VirK/YbjX family protein -
DLD89_RS09390 (DLD89_09390) 1912522..1913175 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
DLD89_RS09395 (DLD89_09395) 1913172..1913363 - 192 WP_002911395.1 YebW family protein -
DLD89_RS09400 (DLD89_09400) 1913461..1913700 - 240 WP_002911393.1 YebV family protein -
DLD89_RS09405 (DLD89_09405) 1913816..1915249 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T267501 NZ_CP115930:1910672-1910774 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT267501 NZ_CP115930:c1910781-1910636 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References