267492

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 318344..318830 Replicon chromosome
Accession NZ_CP115924
Organism Agrobacterium fabacearum strain K224

Toxin (Protein)


Gene name pasB Uniprot ID A0A1S7SNN6
Locus tag G6L41_RS01505 Protein ID WP_019564243.1
Coordinates 318344..318613 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag G6L41_RS01510 Protein ID WP_173992361.1
Coordinates 318597..318830 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L41_RS01475 (G6L41_001475) 313382..314155 - 774 WP_004432233.1 L,D-transpeptidase -
G6L41_RS01480 (G6L41_001480) 314393..315022 + 630 WP_013635543.1 DNA-3-methyladenine glycosylase I -
G6L41_RS01485 (G6L41_001485) 315019..315462 + 444 WP_013635544.1 hypothetical protein -
G6L41_RS01490 (G6L41_001490) 315478..316521 - 1044 WP_019564245.1 YeiH family protein -
G6L41_RS01495 (G6L41_001495) 316604..317521 + 918 WP_065658314.1 LysR family transcriptional regulator -
G6L41_RS01500 (G6L41_001500) 317573..318337 - 765 WP_173992360.1 hypothetical protein -
G6L41_RS01505 (G6L41_001505) 318344..318613 - 270 WP_019564243.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6L41_RS01510 (G6L41_001510) 318597..318830 - 234 WP_173992361.1 DUF6290 family protein Antitoxin
G6L41_RS01515 (G6L41_001515) 318987..320558 + 1572 WP_173992362.1 histidine--tRNA ligase -
G6L41_RS01520 (G6L41_001520) 320568..321695 + 1128 WP_004432209.1 ATP phosphoribosyltransferase regulatory subunit -
G6L41_RS01525 (G6L41_001525) 321692..322384 + 693 WP_004432208.1 ATP phosphoribosyltransferase -
G6L41_RS01530 (G6L41_001530) 322448..322894 - 447 WP_004432207.1 DoxX family protein -
G6L41_RS01535 (G6L41_001535) 323156..323524 - 369 WP_233283634.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10399.94 Da        Isoelectric Point: 9.9971

>T267492 WP_019564243.1 NZ_CP115924:c318613-318344 [Agrobacterium fabacearum]
MTWKIEFQHRAVKQLGKLAKQDANRIVSFLADRVVQDDNPRQTGAALQGSELGSFWRYRVGDYRIICDIQDNKLVVLVVE
IGHRREIYR

Download         Length: 270 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 9211.28 Da        Isoelectric Point: 4.6044

>AT267492 WP_173992361.1 NZ_CP115924:c318830-318597 [Agrobacterium fabacearum]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRQRIANKERTYNLEEVMRDLDVEN

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1S7SNN6

Antitoxin

Source ID Structure

References