Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2937309..2937865 Replicon chromosome
Accession NZ_CP115911
Organism Xanthomonas oryzae pv. oryzae strain NE-8

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag PEV90_RS14035 Protein ID WP_229001948.1
Coordinates 2937309..2937560 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A854CIX2
Locus tag PEV90_RS14040 Protein ID WP_011408759.1
Coordinates 2937587..2937865 (-) Length 93 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PEV90_RS13990 (PEV90_13990) 2933079..2934170 + 1092 WP_011408756.1 ribonuclease D -
PEV90_RS13995 (PEV90_13995) 2934267..2934583 - 317 Protein_2672 ATP-dependent DNA ligase -
PEV90_RS14000 (PEV90_14000) 2934865..2935041 - 177 Protein_2673 DUF3606 domain-containing protein -
PEV90_RS14005 (PEV90_14005) 2935263..2935664 + 402 WP_011259345.1 H-NS family nucleoid-associated regulatory protein -
PEV90_RS14015 (PEV90_14015) 2936095..2936223 - 129 WP_012444694.1 hypothetical protein -
PEV90_RS14020 (PEV90_14020) 2936192..2936311 - 120 Protein_2676 IS3 family transposase -
PEV90_RS14025 (PEV90_14025) 2936528..2936782 - 255 WP_223293127.1 hypothetical protein -
PEV90_RS14030 (PEV90_14030) 2936851..2937048 - 198 WP_153296741.1 hypothetical protein -
PEV90_RS14035 (PEV90_14035) 2937309..2937560 - 252 WP_229001948.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PEV90_RS14040 (PEV90_14040) 2937587..2937865 - 279 WP_011408759.1 CopG family ribbon-helix-helix protein Antitoxin
PEV90_RS14045 (PEV90_14045) 2938061..2938447 - 387 WP_205412094.1 hypothetical protein -
PEV90_RS14050 (PEV90_14050) 2939311..2940495 - 1185 WP_011408397.1 IS256-like element IS1113 family transposase -
PEV90_RS14055 (PEV90_14055) 2941076..2942041 + 966 WP_109181928.1 IS1595-like element ISXo5 family transposase -
PEV90_RS14060 (PEV90_14060) 2942191..2942748 + 558 WP_011259349.1 DNA-3-methyladenine glycosylase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 84 a.a.        Molecular weight: 9603.92 Da        Isoelectric Point: 9.9718

>T267487 WP_229001948.1 NZ_CP115911:c2937560-2937309 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Download         Length: 252 bp


Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10826.11 Da        Isoelectric Point: 4.9736

>AT267487 WP_011408759.1 NZ_CP115911:c2937865-2937587 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A854CIX2

References