Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 141541..142184 Replicon plasmid p277859
Accession NZ_CP115897
Organism Kalamiella piersonii strain URMC-2103A041

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag PG877_RS21845 Protein ID WP_120456617.1
Coordinates 141541..141957 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag PG877_RS21850 Protein ID WP_120456616.1
Coordinates 141954..142184 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG877_RS21835 (PG877_21835) 136988..139390 + 2403 WP_271153539.1 maltodextrin phosphorylase -
PG877_RS21840 (PG877_21840) 139399..141468 + 2070 WP_271153421.1 4-alpha-glucanotransferase -
PG877_RS21845 (PG877_21845) 141541..141957 - 417 WP_120456617.1 type II toxin-antitoxin system VapC family toxin Toxin
PG877_RS21850 (PG877_21850) 141954..142184 - 231 WP_120456616.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PG877_RS21855 (PG877_21855) 142329..143243 - 915 WP_271153422.1 maltose operon protein MalM -
PG877_RS21860 (PG877_21860) 143360..144661 - 1302 WP_120456612.1 maltoporin -
PG877_RS21865 (PG877_21865) 144703..145812 - 1110 WP_120456610.1 maltose/maltodextrin ABC transporter ATP-binding protein MalK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iutA / iucC / hsiC1/vipB 1..277859 277859


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-129)

Antitoxin

SpoVT-AbrB domain

(7-54)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15174.55 Da        Isoelectric Point: 7.1082

>T267481 WP_120456617.1 NZ_CP115897:c141957-141541 [Kalamiella piersonii]
VSKTYMLDTNICSFIMREQPEAVLMRLEQAVLRRDRIVVSAITYAEMRFGAIGKKASPRHAQLVEAFCARLDAILPWDRN
AVDATTEIKAALTAAGNPIGPNDTAIAGHAIATSAILVTNNIKEFERVPGLTFEDWCK

Download         Length: 417 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8967.06 Da        Isoelectric Point: 4.5498

>AT267481 WP_120456616.1 NZ_CP115897:c142184-141954 [Kalamiella piersonii]
MRTVSVFKNGNNRAIRLPRDLDFDGVNELEIIREGDTLLLRPVKPSWRSFREQEKADPDFMTEREEVVSDEGRFEL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References