Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 3455300..3455978 Replicon chromosome
Accession NZ_CP115874
Organism Enterobacter hormaechei subsp. steigerwaltii strain WYTS.MG41

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag PBS85_RS16245 Protein ID WP_265188190.1
Coordinates 3455655..3455978 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag PBS85_RS16240 Protein ID WP_265188191.1
Coordinates 3455300..3455623 (+) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PBS85_RS16210 (PBS85_16210) 3450948..3451388 + 441 WP_265188195.1 hypothetical protein -
PBS85_RS16215 (PBS85_16215) 3451424..3451786 + 363 WP_265188194.1 hypothetical protein -
PBS85_RS16220 (PBS85_16220) 3452110..3453408 - 1299 WP_265188193.1 protein kinase -
PBS85_RS16225 (PBS85_16225) 3453724..3454545 + 822 WP_265188226.1 DUF932 domain-containing protein -
PBS85_RS16230 (PBS85_16230) 3454578..3455048 + 471 WP_265188192.1 DNA repair protein RadC -
PBS85_RS16235 (PBS85_16235) 3455057..3455278 + 222 WP_032642916.1 DUF987 domain-containing protein -
PBS85_RS16240 (PBS85_16240) 3455300..3455623 + 324 WP_265188191.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
PBS85_RS16245 (PBS85_16245) 3455655..3455978 + 324 WP_265188190.1 toxin Toxin
PBS85_RS16250 (PBS85_16250) 3456709..3457947 + 1239 WP_047741185.1 ribokinase -
PBS85_RS16255 (PBS85_16255) 3458069..3458992 + 924 WP_265188189.1 ABC transporter permease subunit -
PBS85_RS16260 (PBS85_16260) 3458992..3459891 + 900 WP_017692842.1 carbohydrate ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3437851..3455978 18127


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-106)

Antitoxin

Antitoxin CbeA

(4-102)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12163.96 Da        Isoelectric Point: 6.6428

>T267452 WP_265188190.1 NZ_CP115874:3455655-3455978 [Enterobacter hormaechei subsp. steigerwaltii]
MHISTVPATVPVSSRLSPVQVWQKLLTYLLEHHYGLTLNDTPFHDDTAIEEHIDAGITLADAVNFLVEKYELARIDRKGF
TWREQPPFITATDILRAKKNIGLLPRS

Download         Length: 324 bp

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 12022.77 Da        Isoelectric Point: 7.3736

>AT267452 WP_265188191.1 NZ_CP115874:3455300-3455623 [Enterobacter hormaechei subsp. steigerwaltii]
MQNSWGLKRDISPCFGARLVQEGCRLHFLANRAGISGAFNEEEALRLDQAFPLVMKQLELMLTTGELNPRHQHCVTLHHN
GLTCEADTLGSHGYVYIVIYPQASKTR

Download         Length: 324 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References