Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 575115..575580 Replicon chromosome
Accession NZ_CP115851
Organism Roseomonas cervicalis strain PL22-11A

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag PFY06_RS02820 Protein ID WP_271136927.1
Coordinates 575350..575580 (+) Length 77 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PFY06_RS02815 Protein ID WP_271136926.1
Coordinates 575115..575363 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PFY06_RS02780 (PFY06_02780) 571385..572338 - 954 WP_271136919.1 phage tail tube protein -
PFY06_RS02785 (PFY06_02785) 572354..572749 - 396 WP_271136920.1 hypothetical protein -
PFY06_RS02790 (PFY06_02790) 572746..573468 - 723 WP_271136921.1 DUF6441 family protein -
PFY06_RS02795 (PFY06_02795) 573469..573735 - 267 WP_271136922.1 DUF6127 family protein -
PFY06_RS02800 (PFY06_02800) 573809..574054 - 246 WP_271136923.1 hypothetical protein -
PFY06_RS02805 (PFY06_02805) 574051..574692 - 642 WP_271136924.1 structural protein -
PFY06_RS02810 (PFY06_02810) 574689..575036 - 348 WP_271136925.1 DUF2190 family protein -
PFY06_RS02815 (PFY06_02815) 575115..575363 + 249 WP_271136926.1 antitoxin MazE family protein Antitoxin
PFY06_RS02820 (PFY06_02820) 575350..575580 + 231 WP_271136927.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PFY06_RS02825 (PFY06_02825) 575724..576746 - 1023 WP_271136928.1 hypothetical protein -
PFY06_RS02830 (PFY06_02830) 576755..577774 - 1020 WP_271136929.1 hypothetical protein -
PFY06_RS02835 (PFY06_02835) 577800..578150 - 351 WP_271136930.1 hypothetical protein -
PFY06_RS02840 (PFY06_02840) 578162..578647 - 486 WP_271136931.1 ubiquitin-activating E1 FCCH domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-75)

Antitoxin

Antitoxin MazE-like

(7-68)


Sequences

Toxin        


Download         Length: 77 a.a.        Molecular weight: 7911.18 Da        Isoelectric Point: 8.0215

>T267438 WP_271136927.1 NZ_CP115851:575350-575580 [Roseomonas cervicalis]
MRRGDIVLIADHSGGDYGSKPRPAVVVQSELFEGTGSVTVCLLTTQLTGAPLLRVPVAPGEGSGLRVPSRIAIEKL

Download         Length: 231 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9301.36 Da        Isoelectric Point: 4.7010

>AT267438 WP_271136926.1 NZ_CP115851:575115-575363 [Roseomonas cervicalis]
MAASDVRKRVAAHRAELRQRGLRPIQIWVPDTRAPGFAEEARRQSQLVAAEADFAETMDFIERVSAFDEGEEDDIPEIHA
PR

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References