Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 385751..386421 Replicon plasmid pAtG3_79a
Accession NZ_CP115843
Organism Agrobacterium fabacearum strain G3/79

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G6L97_RS25070 Protein ID WP_003517201.1
Coordinates 386002..386421 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID F0LGD9
Locus tag G6L97_RS25065 Protein ID WP_003517203.1
Coordinates 385751..386005 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L97_RS25035 (G6L97_25035) 380781..381569 + 789 WP_025591510.1 ABC transporter permease -
G6L97_RS25040 (G6L97_25040) 381571..383079 + 1509 WP_174004087.1 carboxylesterase family protein -
G6L97_RS25045 (G6L97_25045) 383128..384075 + 948 WP_080802808.1 LysR family transcriptional regulator -
G6L97_RS25050 (G6L97_25050) 384232..384540 + 309 WP_112497505.1 hypothetical protein -
G6L97_RS25055 (G6L97_25055) 384779..384985 - 207 WP_025591519.1 hypothetical protein -
G6L97_RS25060 (G6L97_25060) 385236..385463 + 228 Protein_376 acetolactate synthase -
G6L97_RS25065 (G6L97_25065) 385751..386005 + 255 WP_003517203.1 plasmid stabilization protein Antitoxin
G6L97_RS25070 (G6L97_25070) 386002..386421 + 420 WP_003517201.1 type II toxin-antitoxin system VapC family toxin Toxin
G6L97_RS25075 (G6L97_25075) 386648..387544 - 897 WP_174004089.1 dihydrodipicolinate synthase family protein -
G6L97_RS25080 (G6L97_25080) 387577..388458 - 882 WP_111801762.1 SMP-30/gluconolactonase/LRE family protein -
G6L97_RS25085 (G6L97_25085) 388515..389234 - 720 WP_174004091.1 FadR/GntR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..632660 632660


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15036.22 Da        Isoelectric Point: 5.1532

>T267436 WP_003517201.1 NZ_CP115843:386002-386421 [Agrobacterium fabacearum]
MILLDTNVISEPWKPVPDEAVIAWLDAQAVETLFISAITIAELRFGIAAMPSGRRQTILRDRLEGEVLPHFSGRILSFDL
TTSQFYSELMARARASGKAIGTADGYIAATAAANGLTISTRDTSPFEAAGVKVINPWSR

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9253.53 Da        Isoelectric Point: 8.9520

>AT267436 WP_003517203.1 NZ_CP115843:385751-386005 [Agrobacterium fabacearum]
MPAVTIRNLSEETHRALRVRAAHHGRSTEAEIRAIIEAAVRPPERIQLGSLLAAIGRDAELSNSDVEALQKSRDKTPAKP
MTFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F0LGD9

References