Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 241813..242360 Replicon plasmid pAtG3_79a
Accession NZ_CP115843
Organism Agrobacterium fabacearum strain G3/79

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag G6L97_RS24360 Protein ID WP_141194105.1
Coordinates 242067..242360 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID F0LFW5
Locus tag G6L97_RS24355 Protein ID WP_013637268.1
Coordinates 241813..242067 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L97_RS24340 (G6L97_24340) 237360..238202 - 843 WP_065706101.1 MaoC family dehydratase N-terminal domain-containing protein -
G6L97_RS24345 (G6L97_24345) 238275..239357 - 1083 WP_065706102.1 LLM class flavin-dependent oxidoreductase -
G6L97_RS24350 (G6L97_24350) 240379..241617 + 1239 WP_174004015.1 Fic family protein -
G6L97_RS24355 (G6L97_24355) 241813..242067 + 255 WP_013637268.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
G6L97_RS24360 (G6L97_24360) 242067..242360 + 294 WP_141194105.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6L97_RS24365 (G6L97_24365) 242709..243140 - 432 WP_065706103.1 helix-turn-helix domain-containing protein -
G6L97_RS24370 (G6L97_24370) 243268..243564 + 297 WP_003519127.1 YciI family protein -
G6L97_RS24375 (G6L97_24375) 243634..244413 + 780 WP_174004017.1 SDR family oxidoreductase -
G6L97_RS24380 (G6L97_24380) 244493..245308 + 816 WP_174004019.1 oxidoreductase -
G6L97_RS24385 (G6L97_24385) 246117..246341 - 225 WP_198927209.1 NAD(P)-binding domain-containing protein -
G6L97_RS24390 (G6L97_24390) 246598..246909 + 312 WP_038496292.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..632660 632660


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(6-63)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11192.88 Da        Isoelectric Point: 6.2131

>T267435 WP_141194105.1 NZ_CP115843:242067-242360 [Agrobacterium fabacearum]
MPFSLSVQAEEDIISIAEECIRIFGALVARQYHDELFALLELIATNPRMARERHEISPPVRIHPFKAHLVVYRIIEDGSV
FVIRIRHGHEDWAGNSF

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9410.52 Da        Isoelectric Point: 8.5776

>AT267435 WP_013637268.1 NZ_CP115843:241813-242067 [Agrobacterium fabacearum]
MATMNVSLPDPMKDWVEAQAKTGRYSNASDYVRDLIRRDQARTDKIAEMQRFVDDGIRSGVGSRSTEELFALATSRADIS
RGRA

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F0LFW5

References