267433

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 330360..330846 Replicon chromosome
Accession NZ_CP115841
Organism Agrobacterium fabacearum strain G3/79

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag G6L97_RS01580 Protein ID WP_174002647.1
Coordinates 330360..330629 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID A0A1S7SNU1
Locus tag G6L97_RS01585 Protein ID WP_004432214.1
Coordinates 330613..330846 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L97_RS01550 (G6L97_01550) 325398..326171 - 774 WP_004432233.1 L,D-transpeptidase -
G6L97_RS01555 (G6L97_01555) 326409..327038 + 630 WP_111782784.1 DNA-3-methyladenine glycosylase I -
G6L97_RS01560 (G6L97_01560) 327035..327478 + 444 WP_038489949.1 hypothetical protein -
G6L97_RS01565 (G6L97_01565) 327494..328537 - 1044 WP_111782783.1 YeiH family protein -
G6L97_RS01570 (G6L97_01570) 328620..329537 + 918 WP_004432220.1 LysR substrate-binding domain-containing protein -
G6L97_RS01575 (G6L97_01575) 329589..330353 - 765 WP_111782782.1 hypothetical protein -
G6L97_RS01580 (G6L97_01580) 330360..330629 - 270 WP_174002647.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6L97_RS01585 (G6L97_01585) 330613..330846 - 234 WP_004432214.1 DUF6290 family protein Antitoxin
G6L97_RS01590 (G6L97_01590) 331003..332526 + 1524 WP_111782780.1 histidine--tRNA ligase -
G6L97_RS01595 (G6L97_01595) 332531..332899 + 369 WP_111782926.1 VOC family protein -
G6L97_RS01600 (G6L97_01600) 332916..334043 + 1128 WP_111782779.1 ATP phosphoribosyltransferase regulatory subunit -
G6L97_RS01605 (G6L97_01605) 334040..334732 + 693 WP_004432208.1 ATP phosphoribosyltransferase -
G6L97_RS01610 (G6L97_01610) 334796..335242 - 447 WP_013635551.1 DoxX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-88)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10360.92 Da        Isoelectric Point: 9.1353

>T267433 WP_174002647.1 NZ_CP115841:c330629-330360 [Agrobacterium fabacearum]
MTWKIEFQQRAVKQLGKLAKQDANRIVSFLADRVVQDDNPRQTGAALQGSELGSFWRYRVGDYCIICDIQDHKLVVLVVE
IGHRREIYR

Download         Length: 270 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 9225.31 Da        Isoelectric Point: 4.6044

>AT267433 WP_004432214.1 NZ_CP115841:c330846-330613 [Agrobacterium fabacearum]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRQRIANKERTYNLEEVMRDLDLEN

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1S7SNU1

References