Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1896495..1896640 Replicon chromosome
Accession NZ_CP115837
Organism Klebsiella pneumoniae strain MRSN22265

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1896531..1896633 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1896495..1896640 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFB76_RS09235 (KFB76_009235) 1891625..1893685 + 2061 WP_004151449.1 oligopeptidase B -
KFB76_RS09240 (KFB76_009240) 1893689..1894348 - 660 WP_002911407.1 exodeoxyribonuclease X -
KFB76_RS09245 (KFB76_009245) 1894427..1894657 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KFB76_RS09250 (KFB76_009250) 1894770..1895144 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KFB76_RS09255 (KFB76_009255) 1895148..1896017 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
KFB76_RS09260 (KFB76_009260) 1896034..1896372 + 339 WP_002911404.1 YebY family protein -
KFB76_RS09265 (KFB76_009265) 1897008..1897151 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KFB76_RS09270 (KFB76_009270) 1897256..1898224 - 969 WP_004151446.1 VirK/YbjX family protein -
KFB76_RS09275 (KFB76_009275) 1898381..1899034 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KFB76_RS09280 (KFB76_009280) 1899031..1899222 - 192 WP_002911395.1 YebW family protein -
KFB76_RS09285 (KFB76_009285) 1899320..1899559 - 240 WP_002911393.1 YebV family protein -
KFB76_RS09290 (KFB76_009290) 1899675..1901108 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T267422 NZ_CP115837:1896531-1896633 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT267422 NZ_CP115837:c1896640-1896495 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References