Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2014963..2015108 Replicon chromosome
Accession NZ_CP115831
Organism Klebsiella pneumoniae strain L4-FAA5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2014999..2015101 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2014963..2015108 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PGO70_RS09525 2010093..2012153 + 2061 WP_004151449.1 oligopeptidase B -
PGO70_RS09530 2012157..2012816 - 660 WP_032446227.1 exodeoxyribonuclease X -
PGO70_RS09535 2012895..2013125 - 231 WP_002911406.1 DNA polymerase III subunit theta -
PGO70_RS09540 2013238..2013612 + 375 WP_004151448.1 CopC domain-containing protein YobA -
PGO70_RS09545 2013616..2014485 + 870 WP_032446226.1 copper homeostasis membrane protein CopD -
PGO70_RS09550 2014502..2014840 + 339 WP_002911404.1 YebY family protein -
- 2014963..2015108 - 146 - - Antitoxin
- 2014999..2015101 + 103 - - Toxin
PGO70_RS09555 2015476..2015619 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
PGO70_RS09560 2015724..2016692 - 969 WP_004151446.1 VirK/YbjX family protein -
PGO70_RS09565 2016849..2017502 + 654 WP_032446225.1 protein-serine/threonine phosphatase -
PGO70_RS09570 2017499..2017690 - 192 WP_002911395.1 YebW family protein -
PGO70_RS09575 2017788..2018027 - 240 WP_002911393.1 YebV family protein -
PGO70_RS09580 2018143..2019576 - 1434 WP_032446224.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T267401 NZ_CP115831:2014999-2015101 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT267401 NZ_CP115831:c2015108-2014963 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References