267396

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 5308734..5309361 Replicon chromosome
Accession NZ_CP115820
Organism Pseudomonas tohonis strain Q4-3

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag PGN41_RS24515 Protein ID WP_263151077.1
Coordinates 5309179..5309361 (-) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag PGN41_RS24510 Protein ID WP_263151076.1
Coordinates 5308734..5309141 (-) Length 136 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PGN41_RS24500 5306571..5307578 + 1008 WP_271103910.1 nucleoid-associated protein YejK -
PGN41_RS24505 5307636..5308571 - 936 WP_271103911.1 glutathione S-transferase family protein -
PGN41_RS24510 5308734..5309141 - 408 WP_263151076.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
PGN41_RS24515 5309179..5309361 - 183 WP_263151077.1 type II toxin-antitoxin system HicA family toxin Toxin
PGN41_RS24520 5309504..5309812 - 309 WP_271103912.1 GIY-YIG nuclease family protein -
PGN41_RS24525 5309809..5310507 - 699 WP_271103913.1 glutathione S-transferase family protein -
PGN41_RS24530 5310589..5311059 - 471 WP_271103914.1 nuclear transport factor 2 family protein -
PGN41_RS24535 5311176..5312129 + 954 WP_271103915.1 helix-turn-helix domain-containing protein -
PGN41_RS24540 5312583..5313344 - 762 WP_111263764.1 amino acid ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(3-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-127)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6841.90 Da        Isoelectric Point: 10.5627

>T267396 WP_263151077.1 NZ_CP115820:c5309361-5309179 [Pseudomonas tohonis]
MRSREVIEKIKEDGWYEVDVKGSHHQFKHPSKPGRVTVPHPRSDLPIGTVRSILKQAGLL

Download         Length: 183 bp

Antitoxin


Download         Length: 136 a.a.        Molecular weight: 14523.38 Da        Isoelectric Point: 4.3759

>AT267396 WP_263151076.1 NZ_CP115820:c5309141-5308734 [Pseudomonas tohonis]
MKFPIVLHKDPDSDYGVTVPDVPGCFSAGATVAEALENVKEALALHFEGLVADGETLPQAQQIDVYIGNPDFAGGVWAVV
EFDVTPYLGKAVRFNATLPENLLRRIDERVGKDARYASRSGFLATAALRELSDAS

Download         Length: 408 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References