Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 4793769..4794928 Replicon chromosome
Accession NZ_CP115820
Organism Pseudomonas tohonis strain Q4-3

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag PGN41_RS21905 Protein ID WP_213625837.1
Coordinates 4793769..4794521 (-) Length 251 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag PGN41_RS21910 Protein ID WP_271103649.1
Coordinates 4794557..4794928 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PGN41_RS21885 4789479..4790363 + 885 WP_271103647.1 metal-dependent hydrolase -
PGN41_RS21890 4790434..4791798 - 1365 WP_271106364.1 DNA recombination protein RmuC -
PGN41_RS21895 4791962..4792369 - 408 WP_111264581.1 SEL1-like repeat protein -
PGN41_RS21900 4792717..4793772 - 1056 WP_271103648.1 AraC family transcriptional regulator -
PGN41_RS21905 4793769..4794521 - 753 WP_213625837.1 RES family NAD+ phosphorylase Toxin
PGN41_RS21910 4794557..4794928 - 372 WP_271103649.1 DUF2384 domain-containing protein Antitoxin
PGN41_RS21915 4795052..4795534 + 483 WP_263150782.1 transcription elongation factor GreAB -
PGN41_RS21920 4795585..4795998 + 414 WP_271103650.1 hypothetical protein -
PGN41_RS21925 4796192..4796377 + 186 WP_228723486.1 hypothetical protein -
PGN41_RS21930 4796401..4796850 - 450 WP_263150784.1 S24 family peptidase -
PGN41_RS21935 4796952..4798550 - 1599 WP_213625841.1 M28 family metallopeptidase -
PGN41_RS21940 4799044..4799595 + 552 WP_271103651.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(58-206)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(8-68)


Sequences

Toxin        


Download         Length: 251 a.a.        Molecular weight: 28167.20 Da        Isoelectric Point: 7.1064

>T267395 WP_213625837.1 NZ_CP115820:c4794521-4793769 [Pseudomonas tohonis]
MDIWTTCQGPQHIGPLRGRLVRLVESQEQVATLQLVDNLAEQALLEELIETSKPPLPRSAEPLHYLLKTPFRYPPLRWGS
RFGTVHEPSLFYAASRLETAMAEGAFYRFVLWSGMAVPPPSGRILSEHSSFEARFQVERGVQLQLPPFDRHAQALADPVD
YRASQALGAAMRAAGVEAFEYRSARCPLQGTNIALFTPEAFTERRPRNLTPWLCETTAEYVAFKHAQAPDTPRLFRMTQF
LIDGHLPQPA

Download         Length: 753 bp

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13584.81 Da        Isoelectric Point: 10.2920

>AT267395 WP_271103649.1 NZ_CP115820:c4794928-4794557 [Pseudomonas tohonis]
MSALSRPTLDPDAVLAKALLNTREQLGLTQQQLADIVGVHRTAITRWADSGGIRPQSKTGELALLLIRAYRALFALFGGN
LEDMRHFLRTENRHLGAVPLELMGQVQGLVRVVEYLDAIRGKI

Download         Length: 372 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References