Detailed information of TA system TA267394

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Acetyltransf_4(toxin)
• Location: 4780891..4782299
• Replicon: chromosome
• Accession: NZ_CP115820
• Organism: Pseudomonas tohonis strain Q4-3

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PGN41_RS21860
• Protein ID: WP_263150773.1
• Coordinates: 4781730..4782299 (-)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PGN41_RS21855
• Protein ID: WP_271103645.1
• Coordinates: 4780891..4781733 (-)
• Length: 281 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PGN41_RS21830	4776311..4777258	+	948	WP_173171968.1	bile acid:sodium symporter family protein	-
PGN41_RS21835	4777406..4777720	+	315	WP_263150769.1	quaternary ammonium compound efflux SMR transporter SugE	-
PGN41_RS21840	4777784..4779658	-	1875	WP_271103643.1	MFS transporter	-
PGN41_RS21845	4779811..4780140	-	330	WP_111260442.1	AzlD domain-containing protein	-
PGN41_RS21850	4780140..4780853	-	714	WP_271103644.1	AzlC family ABC transporter permease	-
PGN41_RS21855	4780891..4781733	-	843	WP_271103645.1	AraC family transcriptional regulator	Antitoxin
PGN41_RS21860	4781730..4782299	-	570	WP_263150773.1	GNAT family protein	Toxin
PGN41_RS21865	4782551..4786027	+	3477	WP_271103646.1	PAS domain-containing hybrid sensor histidine kinase/response regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (14-146)

Antitoxin

• AraC-type arabinose-binding/dimerisation domain (17-149)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21249.20 Da
• Isoelectric Point: 6.8864

>T267394 WP_263150773.1 NZ_CP115820:c4782299-4781730 [Pseudomonas tohonis]
MFNPQPVILQRGALRLEPLGEADVTELSALAEANRDELVYMSGPLRPDWYRQGLAEQREGQAVVFAIRLGDRLVGTSRFA
DFMPALPAVEIGWTWLARSEHASGLNASIKYLMLRHAFEEWQVVRVQLKTAGSNLRSQKAIEKLGAQREGVLRNHRRLAD
GRLDDSVLYSITDHEWPAVKQALEASFGQ

Nucleotide

• Length: 570 bp

Antitoxin

Protein

• Length: 281 a.a.
• Molecular weight: 31246.56 Da
• Isoelectric Point: 9.4274

>AT267394 WP_271103645.1 NZ_CP115820:c4781733-4780891 [Pseudomonas tohonis]
MSTGGERTRFWQASALGGVELLHARYIEQRFSPHVHEGYVFTVLESGAQRFRHRGSDHLAAVGSMVLINPDELHTGSKAH
EEGWRYRGFYPDLHRVTEVLDELEIATGGLPTFADSVLHDPEVTRRFLDLHRLLERNASALEQQVAWREAILLLFSRHAR
IGAPRPAGQEPQAVALAREVLAARLASPPSLEELAALVGLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLREGCAPL
PVAMQLGFADQSHLTRQFKQAYGVGPGEYRSACARSFKTG

Nucleotide

• Length: 843 bp