Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/-
Location 4431242..4431854 Replicon chromosome
Accession NZ_CP115820
Organism Pseudomonas tohonis strain Q4-3

Toxin (Protein)


Gene name PfiT Uniprot ID -
Locus tag PGN41_RS20190 Protein ID WP_271103490.1
Coordinates 4431510..4431854 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID -
Locus tag PGN41_RS20185 Protein ID WP_271103489.1
Coordinates 4431242..4431526 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PGN41_RS20165 4426652..4427950 - 1299 WP_263154481.1 cobyrinate a,c-diamide synthase -
PGN41_RS20170 4427947..4428558 - 612 WP_173177993.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
PGN41_RS20175 4428570..4430405 - 1836 WP_271106349.1 TonB-dependent vitamin B12 receptor -
PGN41_RS20180 4430824..4431159 + 336 WP_213625600.1 four-helix bundle copper-binding protein -
PGN41_RS20185 4431242..4431526 + 285 WP_271103489.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PGN41_RS20190 4431510..4431854 + 345 WP_271103490.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PGN41_RS20195 4431864..4432184 - 321 WP_213625601.1 hypothetical protein -
PGN41_RS20200 4432189..4432851 - 663 WP_271103491.1 class I SAM-dependent methyltransferase -
PGN41_RS20205 4432860..4433387 - 528 WP_111262051.1 C40 family peptidase -
PGN41_RS20210 4433562..4434173 - 612 WP_271103492.1 C40 family peptidase -
PGN41_RS20215 4434240..4435013 - 774 WP_263150450.1 NAD-dependent deacylase -
PGN41_RS20220 4435041..4435712 - 672 WP_271103493.1 DNA-3-methyladenine glycosylase I -
PGN41_RS20225 4435820..4436644 - 825 WP_213625605.1 tRNA 2-thiocytidine(32) synthetase TtcA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-101)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12948.98 Da        Isoelectric Point: 6.4846

>T267393 WP_271103490.1 NZ_CP115820:4431510-4431854 [Pseudomonas tohonis]
MSRTIEVAYATTAEESLISQIHHLTPFLGAEQAYAKLATLIKSAERHLKAHPLAAPVCEQAALLGVRGYHELHIEEFRIL
YRYDDAASLVMVALVLRQRQSIEEQLINYCLMRE

Download         Length: 345 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10499.87 Da        Isoelectric Point: 7.0136

>AT267393 WP_271103489.1 NZ_CP115820:4431242-4431526 [Pseudomonas tohonis]
MKVRTISYLKQHAASLDLSEPMVITQNGVPAYVVESYAERRRRDEALALIKLLSFAERDKAEGRLISSDSLLQRLKQRSP
VAQGPGESGDEQND

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References