Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 3911243..3911876 Replicon chromosome
Accession NZ_CP115820
Organism Pseudomonas tohonis strain Q4-3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PGN41_RS17680 Protein ID WP_263150043.1
Coordinates 3911243..3911614 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PGN41_RS17685 Protein ID WP_263150045.1
Coordinates 3911640..3911876 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PGN41_RS17645 3906380..3906652 + 273 WP_021217973.1 DUF2282 domain-containing protein -
PGN41_RS17650 3906669..3907508 + 840 WP_271103238.1 DUF692 domain-containing protein -
PGN41_RS17655 3907505..3908290 + 786 WP_271103239.1 DNA-binding domain-containing protein -
PGN41_RS17660 3908304..3908768 + 465 WP_271103240.1 DoxX family protein -
PGN41_RS17665 3908776..3909372 - 597 WP_244862907.1 chalcone isomerase family protein -
PGN41_RS17670 3909446..3910342 - 897 WP_263150040.1 alpha/beta hydrolase -
PGN41_RS17675 3910467..3911234 + 768 WP_271103241.1 DUF2092 domain-containing protein -
PGN41_RS17680 3911243..3911614 - 372 WP_263150043.1 PIN domain-containing protein Toxin
PGN41_RS17685 3911640..3911876 - 237 WP_263150045.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PGN41_RS17690 3912016..3912648 + 633 WP_271103242.1 hypothetical protein -
PGN41_RS17695 3912821..3913735 - 915 WP_271103243.1 LysR family transcriptional regulator -
PGN41_RS17700 3913895..3915232 + 1338 WP_271103244.1 nucleobase:cation symporter-2 family protein -
PGN41_RS17705 3915272..3915778 + 507 WP_271103245.1 nucleoside deaminase -
PGN41_RS17710 3915775..3916131 + 357 WP_263150052.1 hydroxyisourate hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-105)

Antitoxin

SpoVT-AbrB domain

(5-45)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13568.81 Da        Isoelectric Point: 7.1892

>T267392 WP_263150043.1 NZ_CP115820:c3911614-3911243 [Pseudomonas tohonis]
VLLYLLSADPAKADAAEALLAKRPTISVQVLNEVASVCSRKLRMSWDEIGRFLELVQGFCRVVPVTLEIHRQARELAERY
RLSFYDACIAAAALVAGCSTLHSEDMHSGLLLDGRLRVLNPFG

Download         Length: 372 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8785.90 Da        Isoelectric Point: 4.6838

>AT267392 WP_263150045.1 NZ_CP115820:c3911876-3911640 [Pseudomonas tohonis]
MQVAKWGNSLAVRIPASVVEALELKEGDDIEILIEGDRTFAISKKPDDEGRLARLRAFRGKLPADFRFNRDEDAGRED

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References