Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2528581..2529834 Replicon chromosome
Accession NZ_CP115820
Organism Pseudomonas tohonis strain Q4-3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PGN41_RS11675 Protein ID WP_271105764.1
Coordinates 2529250..2529834 (+) Length 195 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PGN41_RS11670 Protein ID WP_271105763.1
Coordinates 2528581..2529138 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PGN41_RS11650 2524126..2524737 + 612 WP_173174526.1 LysE family translocator -
PGN41_RS11655 2524740..2526827 - 2088 WP_263153892.1 PAS domain S-box protein -
PGN41_RS11660 2527012..2527761 + 750 WP_271105761.1 NAD-dependent deacylase -
PGN41_RS11665 2527788..2528303 - 516 WP_271105762.1 thioredoxin family protein -
PGN41_RS11670 2528581..2529138 + 558 WP_271105763.1 helix-turn-helix transcriptional regulator Antitoxin
PGN41_RS11675 2529250..2529834 + 585 WP_271105764.1 HD domain-containing protein Toxin
PGN41_RS11680 2530045..2530428 + 384 WP_263153898.1 cytochrome c -
PGN41_RS11685 2530454..2530594 - 141 WP_111261604.1 DUF2256 domain-containing protein -
PGN41_RS11690 2530591..2532132 - 1542 WP_271105765.1 cryptochrome/photolyase family protein -
PGN41_RS11695 2532129..2532434 - 306 WP_263153900.1 DUF6482 family protein -
PGN41_RS11700 2532465..2533001 - 537 WP_271105766.1 DUF3833 domain-containing protein -
PGN41_RS11705 2533013..2533564 - 552 WP_271105767.1 chalcone isomerase family protein -
PGN41_RS11710 2533793..2534749 + 957 WP_173174505.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(7-189)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-67)


Sequences

Toxin        


Download         Length: 195 a.a.        Molecular weight: 21631.29 Da        Isoelectric Point: 4.7781

>T267391 WP_271105764.1 NZ_CP115820:2529250-2529834 [Pseudomonas tohonis]
MNIDTIRARLDFLREAERLKDVLRSAHTSSGRAESTAEHSWRLCLMAITFADELAGLDLLRVLKMCVVHDLGEAIHGDIP
AVEQGGHPDKGAREREDLLTLTRTLDDGLRGEILALWDDYENAASPEALAVKALDKLETLLQHTQGANPEDFDYAFNLGY
GRRYTSGEPLFAAIRAQLDEDTRRRMEAQASAAR

Download         Length: 585 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20262.43 Da        Isoelectric Point: 9.4428

>AT267391 WP_271105763.1 NZ_CP115820:2528581-2529138 [Pseudomonas tohonis]
MHDSLPKPVSLGLALRRWRLLHRVKQAHAAQLFGVAQSTISRWESGAQAMEPAERARVEQVLGARLEAAADQALARLVGD
SPRAVHLVCDLSHRLLACSALRAAEFSVPLSELLGRSLWRYATPEIVRKEAALDALGWRDVLMPPALEFGSGSNESAIVP
IRQGLCRWTRMTLSDGTAARLVETL

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References