Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 1805313..1805902 Replicon chromosome
Accession NZ_CP115820
Organism Pseudomonas tohonis strain Q4-3

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PGN41_RS08495 Protein ID WP_263153316.1
Coordinates 1805313..1805612 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PGN41_RS08500 Protein ID WP_271105376.1
Coordinates 1805609..1805902 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PGN41_RS08465 1800480..1802015 + 1536 WP_263153313.1 DHA2 family efflux MFS transporter permease subunit -
PGN41_RS08475 1802419..1802640 - 222 WP_021219560.1 YgdI/YgdR family lipoprotein -
PGN41_RS08480 1802725..1803312 - 588 WP_271105374.1 molybdenum cofactor guanylyltransferase MobA -
PGN41_RS08485 1803385..1803924 + 540 WP_173173724.1 molybdenum cofactor biosynthesis protein B -
PGN41_RS08490 1803921..1805135 + 1215 WP_213628903.1 molybdopterin molybdotransferase MoeA -
PGN41_RS08495 1805313..1805612 + 300 WP_263153316.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PGN41_RS08500 1805609..1805902 + 294 WP_271105376.1 putative addiction module antidote protein Antitoxin
PGN41_RS08505 1805903..1806925 - 1023 WP_263153319.1 AraC family transcriptional regulator -
PGN41_RS08510 1807058..1808653 + 1596 WP_271105377.1 FAD-binding oxidoreductase -
PGN41_RS08515 1808656..1810233 + 1578 WP_271105378.1 glycerol-3-phosphate dehydrogenase/oxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(12-93)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11092.73 Da        Isoelectric Point: 11.1304

>T267390 WP_263153316.1 NZ_CP115820:1805313-1805612 [Pseudomonas tohonis]
MITIRQTATFAAWERKLKDRKARAAIAARIFRLANGLPGDVAPVGQGVSEMRINYGPGYRVYFQQRGNELVILLCGGDKS
SQGRDIEQARRLAAEWRSQ

Download         Length: 300 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10340.84 Da        Isoelectric Point: 4.5680

>AT267390 WP_271105376.1 NZ_CP115820:1805609-1805902 [Pseudomonas tohonis]
MMEELYGYDPAEALGSPEAIAVFVADALETGDAAYIAKAMGVVARAKGMTELARETGLSREQLYRSFSDQGNPTLRTMLA
VMRALGLDMTAKPHSAA

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References