267388

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE-Phd
Location 3387..3986 Replicon plasmid pHN21SC3150TT-1
Accession NZ_CP115818
Organism Pseudomonas mendocina strain GD22SC3150TT

Toxin (Protein)


Gene name PfiT Uniprot ID -
Locus tag PAK23_RS20745 Protein ID WP_276489365.1
Coordinates 3648..3986 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID -
Locus tag PAK23_RS20740 Protein ID WP_102839343.1
Coordinates 3387..3635 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAK23_RS20725 84..1643 + 1560 WP_256825318.1 PAS domain-containing methyl-accepting chemotaxis protein -
PAK23_RS20730 1796..2680 - 885 WP_276489363.1 Y-family DNA polymerase -
PAK23_RS20735 2688..3119 - 432 WP_276489364.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
PAK23_RS20740 3387..3635 + 249 WP_102839343.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PAK23_RS20745 3648..3986 + 339 WP_276489365.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PAK23_RS20750 4266..4955 + 690 WP_276489366.1 NYN domain-containing protein -
PAK23_RS20755 5470..6111 + 642 WP_276489367.1 AAA family ATPase -
PAK23_RS20760 6108..6425 + 318 WP_276489368.1 hypothetical protein -
PAK23_RS20765 6718..7776 + 1059 WP_276489369.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid qnrVC1 / aac(6')-IIa / floR / tet(G) - 1..35410 35410


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-94)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12705.41 Da        Isoelectric Point: 4.4829

>T267388 WP_276489365.1 NZ_CP115818:3648-3986 [Pseudomonas mendocina]
MTTFDVRFTDSASQSIEDQVHHLAVYQGTEAALARIDSLVDVITDKLKSTPMGYPVSQQASELGIIHYRELNTDGYRILY
EIFDTDIAVELVIRQKQSVEQALIRYCLLNPL

Download         Length: 339 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9312.66 Da        Isoelectric Point: 8.9265

>AT267388 WP_102839343.1 NZ_CP115818:3387-3635 [Pseudomonas mendocina]
MRVETISYLKRHAADLDLDEPMVVTQNGVPAYVVESYADRKRRDEAIALVKLLAIGSREYAQGKHCSADELKARLARRFA
QH

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References