Detailed information of TA system TA267387

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Acetyltransf_4(toxin)
• Location: 3257571..3258973
• Replicon: chromosome
• Accession: NZ_CP115817
• Organism: Pseudomonas mendocina strain GD22SC3150TT

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PAK23_RS15275
• Protein ID: WP_276487198.1
• Coordinates: 3258404..3258973 (-)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PAK23_RS15270
• Protein ID: WP_183893762.1
• Coordinates: 3257571..3258398 (-)
• Length: 276 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PAK23_RS15255	3254483..3255388	-	906	WP_183893768.1	GIDE domain-containing protein	-
PAK23_RS15260	3255399..3255971	-	573	WP_183893766.1	LemA family protein	-
PAK23_RS15265	3256163..3257500	+	1338	WP_276487197.1	imelysin family protein	-
PAK23_RS15270	3257571..3258398	-	828	WP_183893762.1	AraC family transcriptional regulator	Antitoxin
PAK23_RS15275	3258404..3258973	-	570	WP_276487198.1	GNAT family protein	Toxin
PAK23_RS15280	3259188..3262676	+	3489	WP_276487199.1	PAS domain-containing hybrid sensor histidine kinase/response regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (14-146)

Antitoxin

• AraC-type arabinose-binding/dimerisation domain (17-142)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21633.72 Da
• Isoelectric Point: 8.0478

>T267387 WP_276487198.1 NZ_CP115817:c3258973-3258404 [Pseudomonas mendocina]
MFKPQLVTLQRGALRLEPLSDTDIPALVALAETNREELLYMSGTQRLDWYRSALTDLREQRALPFVIRLGDELVGTTRFA
DFMNTLPACEIGWTWIDRNQHGSGLNTTIKYLMLKHAFDNWGMVRVQLKTAASNLRSQRAIEKLGAVREGRLRNHRRLAD
GRLDDTVLYSITDQEWPALRENMESGFGA

Nucleotide

• Length: 570 bp

Antitoxin

Protein

• Length: 276 a.a.
• Molecular weight: 30874.16 Da
• Isoelectric Point: 9.9908

>AT267387 WP_183893762.1 NZ_CP115817:c3258398-3257571 [Pseudomonas mendocina]
MQSREQTRFWQASALSGVELLQARYLEQRFAPHVHEGFVFTVIEHGAQRFRHRGSDHLAPQGSMVLINPDEVHTGSKAHE
DGWRYRGFYPGNAQVLGALQELGLAKSGMPSFPFSVLHDPQLHSAFLQLHRLLDDGAEALQQQLAWREAILLLFQRHARL
AEPRAPGREPWAVACAKQMLAERLIEPPTLEELAAAVNLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLKTGCTAVT
AATQLGFADQSHLSRQFKQAYGVSPGEYRNAVARS

Nucleotide

• Length: 828 bp