267386

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 1210532..1212124 Replicon chromosome
Accession NZ_CP115817
Organism Pseudomonas mendocina strain GD22SC3150TT

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag PAK23_RS05610 Protein ID WP_276488659.1
Coordinates 1210532..1211857 (+) Length 442 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag PAK23_RS05615 Protein ID WP_276488660.1
Coordinates 1211858..1212124 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAK23_RS05590 1206161..1207072 + 912 WP_276488656.1 LysR family transcriptional regulator -
PAK23_RS05595 1207069..1207662 - 594 WP_276488657.1 nucleotidyltransferase family protein -
PAK23_RS05600 1207665..1209863 - 2199 WP_276488658.1 OsmC domain/YcaO domain-containing protein -
PAK23_RS05605 1210009..1210152 - 144 Protein_1108 IS3 family transposase -
PAK23_RS05610 1210532..1211857 + 1326 WP_276488659.1 HipA domain-containing protein Toxin
PAK23_RS05615 1211858..1212124 + 267 WP_276488660.1 helix-turn-helix transcriptional regulator Antitoxin
PAK23_RS05620 1212639..1212881 - 243 WP_134307309.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
PAK23_RS05625 1212878..1213726 - 849 WP_121142433.1 inositol monophosphatase family protein -
PAK23_RS05630 1213716..1215077 - 1362 WP_089030861.1 Fic family protein -
PAK23_RS05635 1215406..1216542 - 1137 WP_276488661.1 DUF3883 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(166-383)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 442 a.a.        Molecular weight: 49174.85 Da        Isoelectric Point: 4.7814

>T267386 WP_276488659.1 NZ_CP115817:1210532-1211857 [Pseudomonas mendocina]
MHNLTLQVYTDGQWRDAMAICFEQPEEGLEGVCAYGYQQGYLVDSLEFVGNRLNVAVSAAYPLGWDSWRDKKAPAFLLDI
LPSGAARRFLLKRLGGERPEGLNLDLYLLGRCTPAPIGNLRIKESVEAIAGSPVLGFTRDEVISRDVRFLEYAYEQGAAI
GGATGAGGEAPKLLLTEDRQGALHPDAVLPDADAAQHWFVKFARNKASQTDQDILRSEYCFYRAVQQLGIDTVAAEGLAL
EEGNKPSLWMHRFDREVGPAGVSRTAVESMYSLCGVTEAGSYMLHTQVLEKLVELWRAVGQEQQVGDLIFEYMRRDLLNQ
ILGNSDNHGRNTAILRCEQGVRLAPIYDLAPMVMDEEGVTRTTKWPKHIELAGEVNWRAACDEVSEWVDADDLFQRLRLA
AQEFLALPDLLSAEGLPDSTMTHPRIALRNLRQRMLHWGLV

Download         Length: 1326 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9956.59 Da        Isoelectric Point: 10.9502

>AT267386 WP_276488660.1 NZ_CP115817:1211858-1212124 [Pseudomonas mendocina]
MDILERNRILNELQQQLASGEITIGGAVRRLRKEVTGLQQARFAQMCKLSLRALRQLELDESNPTVQTLNNVFNPFGMQV
GIVPKPPR

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References