Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RHH
Location 624636..625192 Replicon chromosome
Accession NZ_CP115784
Organism Paracoccus aerodenitrificans strain SCSIO 75817

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PAE61_RS04365 Protein ID WP_101754684.1
Coordinates 624636..624944 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PAE61_RS04370 Protein ID WP_271114192.1
Coordinates 624941..625192 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAE61_RS04355 (PAE61_04365) 620108..622735 + 2628 WP_271114190.1 nitrate reductase -
PAE61_RS04360 (PAE61_04370) 623074..624414 - 1341 WP_271114191.1 hypothetical protein -
PAE61_RS04365 (PAE61_04375) 624636..624944 - 309 WP_101754684.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PAE61_RS04370 (PAE61_04380) 624941..625192 - 252 WP_271114192.1 hypothetical protein Antitoxin
PAE61_RS04375 (PAE61_04385) 625357..625629 + 273 WP_271114193.1 hypothetical protein -
PAE61_RS04380 (PAE61_04390) 625673..626254 + 582 WP_232816720.1 SOS response-associated peptidase family protein -
PAE61_RS04385 (PAE61_04395) 626903..628096 - 1194 WP_252734076.1 acyl-CoA dehydrogenase -
PAE61_RS04390 (PAE61_04400) 628187..629842 - 1656 WP_271071071.1 electron transfer flavoprotein-ubiquinone oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 588836..847920 259084


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11144.79 Da        Isoelectric Point: 7.0119

>T267383 WP_101754684.1 NZ_CP115784:c624944-624636 [Paracoccus aerodenitrificans]
MKTLLIAEPAGRDLEAIVDYIARENPAAAENVYRQIARTAAKLPEFPALGRPGRFSGTREMNVAGSPYLIVYEVNVEAVT
ILAVFHTSRNLAAALRDRMEGS

Download         Length: 309 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9022.09 Da        Isoelectric Point: 4.6855

>AT267383 WP_271114192.1 NZ_CP115784:c625192-624941 [Paracoccus aerodenitrificans]
MPQRAETELMTVRTARVSEIDALAAAMDRSRNYVVNQAIDQFLEANAWQMERIAAGVAAAREGNVSSADDVFGAIATKHG
WQA

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References