Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 180841..181376 Replicon chromosome
Accession NZ_CP115784
Organism Paracoccus aerodenitrificans strain SCSIO 75817

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag PAE61_RS02110 Protein ID WP_271113788.1
Coordinates 180841..181131 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag PAE61_RS02115 Protein ID WP_271113789.1
Coordinates 181131..181376 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAE61_RS02100 (PAE61_02110) 178690..180168 - 1479 WP_271113786.1 DNA polymerase Y family protein -
PAE61_RS02105 (PAE61_02115) 180110..180658 - 549 WP_271113787.1 hypothetical protein -
PAE61_RS02110 (PAE61_02120) 180841..181131 - 291 WP_271113788.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PAE61_RS02115 (PAE61_02125) 181131..181376 - 246 WP_271113789.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
PAE61_RS02120 (PAE61_02130) 181500..182135 + 636 WP_271113790.1 tyrosine-type recombinase/integrase -
PAE61_RS02125 (PAE61_02135) 182270..183163 - 894 WP_271113791.1 aldo/keto reductase -
PAE61_RS02130 (PAE61_02140) 183176..184036 - 861 WP_271113792.1 aldo/keto reductase -
PAE61_RS02135 (PAE61_02145) 184072..184818 - 747 WP_271113793.1 glucose 1-dehydrogenase -
PAE61_RS02140 (PAE61_02150) 184838..185329 - 492 WP_271113794.1 DUF4440 domain-containing protein -
PAE61_RS02145 (PAE61_02155) 185388..186368 - 981 WP_271113795.1 quinone oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11241.92 Da        Isoelectric Point: 7.2755

>T267382 WP_271113788.1 NZ_CP115784:c181131-180841 [Paracoccus aerodenitrificans]
MTSSYLLTPLAETDLEEIWLYTARRWSPEQAEIYTNDIIDACEDLVSGRKSGRPVAIRDGYFKTMAGRHIIYFQRRAETL
LVVRILHQRMDIKSHL

Download         Length: 291 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8858.95 Da        Isoelectric Point: 8.7037

>AT267382 WP_271113789.1 NZ_CP115784:c181376-181131 [Paracoccus aerodenitrificans]
MAKNTSMSLGDHFAGFIESQVSNGRYGSASEVVRAGLRLLEEQEAKVQALKDALIAGENSGVPRPLDRDAFQARMRQKHQ
S

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References