Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 87951..88416 Replicon plasmid p1
Accession NZ_CP115780
Organism Paracoccus aerodenitrificans strain SCSIO 75817

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag PAE61_RS00475 Protein ID WP_271109802.1
Coordinates 88153..88416 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag PAE61_RS00470 Protein ID WP_271109801.1
Coordinates 87951..88166 (-) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAE61_RS00435 (PAE61_00435) 83311..84465 - 1155 WP_271112124.1 lytic transglycosylase domain-containing protein -
PAE61_RS00440 (PAE61_00440) 84455..84622 - 168 WP_170317860.1 hypothetical protein -
PAE61_RS00445 (PAE61_00445) 84619..85248 - 630 Protein_88 type IV secretion system protein B4 -
PAE61_RS00450 (PAE61_00450) 85317..86030 + 714 WP_271109796.1 IS6 family transposase -
PAE61_RS00455 (PAE61_00455) 86224..86754 + 531 WP_271109798.1 MarR family transcriptional regulator -
PAE61_RS00460 (PAE61_00460) 86751..87527 + 777 WP_271112125.1 DNA alkylation repair protein -
PAE61_RS00465 (PAE61_00465) 87548..87886 + 339 WP_271109800.1 hypothetical protein -
PAE61_RS00470 (PAE61_00470) 87951..88166 - 216 WP_271109801.1 hypothetical protein Antitoxin
PAE61_RS00475 (PAE61_00475) 88153..88416 - 264 WP_271109802.1 BrnT family toxin Toxin
PAE61_RS00480 (PAE61_00480) 88692..89729 + 1038 WP_036743765.1 IS110 family transposase -
PAE61_RS00485 (PAE61_00485) 90054..91082 + 1029 WP_009803435.1 IS110 family transposase -
PAE61_RS00490 (PAE61_00490) 91399..92331 + 933 WP_271109803.1 IS5-like element ISPko1 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..198273 198273


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 9975.16 Da        Isoelectric Point: 5.1358

>T267380 WP_271109802.1 NZ_CP115780:c88416-88153 [Paracoccus aerodenitrificans]
MDFEYDPAKSASNLSKHGIDFDQAQALWDDPWMLEAPAKTEDEPRLISIGKIEGKHWAAVWTPRGNAVRIISVRRARKEE
ISYYEGN

Download         Length: 264 bp

>T267380 NZ_CP115780:c88416-88153 [Paracoccus aerodenitrificans]
ATGGATTTTGAGTATGACCCCGCCAAAAGTGCCTCGAATCTGTCGAAGCATGGCATCGACTTCGATCAGGCACAGGCTCT
TTGGGATGACCCGTGGATGCTCGAAGCGCCCGCCAAGACCGAGGATGAACCGCGGCTCATCTCGATTGGGAAGATCGAGG
GCAAGCACTGGGCAGCCGTCTGGACGCCGCGAGGTAATGCGGTGCGGATCATCTCGGTGCGCCGCGCCCGAAAAGAGGAG
ATCAGCTACTATGAAGGCAACTGA

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8309.37 Da        Isoelectric Point: 7.0124

>AT267380 WP_271109801.1 NZ_CP115780:c88166-87951 [Paracoccus aerodenitrificans]
MKATEFDKKFDTDENVSDAIDWSQARRPNDQPKRVNVDFPAWVVEGLDKQARHLGVTRQSLIKLWIAERLQ

Download         Length: 216 bp

>AT267380 NZ_CP115780:c88166-87951 [Paracoccus aerodenitrificans]
ATGAAGGCAACTGAGTTCGATAAGAAATTCGACACCGATGAGAACGTGAGCGATGCAATCGACTGGTCCCAGGCGCGGCG
TCCGAACGACCAACCCAAGCGCGTGAACGTGGATTTTCCGGCGTGGGTCGTCGAGGGCCTCGACAAGCAGGCTCGGCACT
TGGGCGTGACGCGGCAATCGCTAATCAAGCTATGGATTGCCGAACGGCTCCAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References