Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 6822..7858 | Replicon | plasmid p3 |
| Accession | NZ_CP115778 | ||
| Organism | Paracoccus albus strain SCSIO 80058 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | PAF20_RS18280 | Protein ID | WP_009179450.1 |
| Coordinates | 7283..7858 (+) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | PAF20_RS18275 | Protein ID | WP_271073657.1 |
| Coordinates | 6822..7286 (+) | Length | 155 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PAF20_RS18255 (PAF20_18255) | 2671..3951 | + | 1281 | WP_271073653.1 | plasmid replication protein RepC | - |
| PAF20_RS18260 (PAF20_18260) | 3964..5079 | - | 1116 | WP_271073654.1 | tyrosine-type recombinase/integrase | - |
| PAF20_RS18265 (PAF20_18265) | 5205..6089 | + | 885 | WP_271073655.1 | DUF1403 family protein | - |
| PAF20_RS18270 (PAF20_18270) | 6092..6688 | + | 597 | WP_271073656.1 | SMC-Scp complex subunit ScpB | - |
| PAF20_RS18275 (PAF20_18275) | 6822..7286 | + | 465 | WP_271073657.1 | helix-turn-helix domain-containing protein | Antitoxin |
| PAF20_RS18280 (PAF20_18280) | 7283..7858 | + | 576 | WP_009179450.1 | PIN domain-containing protein | Toxin |
| PAF20_RS18285 (PAF20_18285) | 7911..8627 | - | 717 | WP_009179413.1 | SprT family zinc-dependent metalloprotease | - |
| PAF20_RS18290 (PAF20_18290) | 8624..11848 | - | 3225 | WP_271073658.1 | type I restriction endonuclease subunit R | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..82828 | 82828 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 20903.78 Da Isoelectric Point: 4.4829
>T267379 WP_009179450.1 NZ_CP115778:7283-7858 [Paracoccus albus]
MSRYADRFTALLDACVLGGALRRNMLLSLAEAGLFRPRWSSRILDETQKAITQITKGETDGSRQRAAIEAAFPEALVTGY
EIFEEKLALPDPNDNHVLAAAIATSASVIVTDNLADFPSAVLDPHAIQAISADDFIADTIELDPSEAILALRRMRERFKN
PALDVAALIHKSEAQGLLQVATFMDEYQSFL
MSRYADRFTALLDACVLGGALRRNMLLSLAEAGLFRPRWSSRILDETQKAITQITKGETDGSRQRAAIEAAFPEALVTGY
EIFEEKLALPDPNDNHVLAAAIATSASVIVTDNLADFPSAVLDPHAIQAISADDFIADTIELDPSEAILALRRMRERFKN
PALDVAALIHKSEAQGLLQVATFMDEYQSFL
Download Length: 576 bp
Antitoxin
Download Length: 155 a.a. Molecular weight: 16978.46 Da Isoelectric Point: 5.1019
>AT267379 WP_271073657.1 NZ_CP115778:6822-7286 [Paracoccus albus]
MNALRKEAFFDRLPDEVEIKNAEQLRTIVASQIKEGEPTKLSLALEGGEVRTVTLAPALTASLLEVLRLVSSGRGFRMIP
VESELTTQQAADLLNVSRPFLVKLLEEGEIPFAKTGRHRRVRADDLFAYKEKRDASRSDALSGLAAMDAEEGLV
MNALRKEAFFDRLPDEVEIKNAEQLRTIVASQIKEGEPTKLSLALEGGEVRTVTLAPALTASLLEVLRLVSSGRGFRMIP
VESELTTQQAADLLNVSRPFLVKLLEEGEIPFAKTGRHRRVRADDLFAYKEKRDASRSDALSGLAAMDAEEGLV
Download Length: 465 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|