Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 66443..67070 Replicon plasmid p2
Accession NZ_CP115777
Organism Paracoccus albus strain SCSIO 80058

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PAF20_RS18015 Protein ID WP_271073554.1
Coordinates 66663..67070 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PAF20_RS18010 Protein ID WP_271073553.1
Coordinates 66443..66673 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAF20_RS17990 (PAF20_17990) 61948..62628 - 681 WP_271073549.1 hypothetical protein -
PAF20_RS17995 (PAF20_17995) 62628..63344 - 717 WP_271073550.1 AAA family ATPase -
PAF20_RS18000 (PAF20_18000) 63924..64529 + 606 WP_271073551.1 plasmid mobilization relaxosome protein MobC -
PAF20_RS18005 (PAF20_18005) 64526..66364 + 1839 WP_271073552.1 relaxase/mobilization nuclease domain-containing protein -
PAF20_RS18010 (PAF20_18010) 66443..66673 + 231 WP_271073553.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PAF20_RS18015 (PAF20_18015) 66663..67070 + 408 WP_271073554.1 PIN domain-containing protein Toxin
PAF20_RS18020 (PAF20_18020) 67941..68972 + 1032 WP_271073555.1 ATP-binding protein -
PAF20_RS18025 (PAF20_18025) 68950..71529 + 2580 WP_271073556.1 S8 family peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..111649 111649


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-116)

Antitoxin

Antitoxin PemI-like

(2-43)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15035.19 Da        Isoelectric Point: 4.3660

>T267378 WP_271073554.1 NZ_CP115777:66663-67070 [Paracoccus albus]
MPGRFFDTNILLYLFSDDRAKADIAEGLLRDGGTVSVQVLNEIANVTQRKFKMSWSQSDEFLLMIREFVTVEPLTYETHD
LGIALARKHTLSVYDAMIVAAGLLAGCDTVLSEDMQDGFRVADRITISNPFAALE

Download         Length: 408 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8767.03 Da        Isoelectric Point: 10.0754

>AT267378 WP_271073553.1 NZ_CP115777:66443-66673 [Paracoccus albus]
MQIAKWGNSLAVRLPARMVQELGLKAGDEIEITATDAGHFQVQRRRDPEEILARLREFRGLMPKGYRFDRDEANAR

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References