Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 183868..184520 Replicon plasmid p1
Accession NZ_CP115776
Organism Paracoccus albus strain SCSIO 80058

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PAF20_RS17530 Protein ID WP_271073428.1
Coordinates 183868..184272 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PAF20_RS17535 Protein ID WP_271073429.1
Coordinates 184272..184520 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAF20_RS17500 (PAF20_17500) 179766..180404 + 639 WP_271073423.1 CDP-alcohol phosphatidyltransferase family protein -
PAF20_RS17505 (PAF20_17505) 180524..181420 + 897 WP_271073424.1 2-dehydro-3-deoxygalactonokinase -
PAF20_RS17510 (PAF20_17510) 181417..182025 + 609 WP_271073425.1 2-dehydro-3-deoxy-6-phosphogalactonate aldolase -
PAF20_RS17515 (PAF20_17515) 182030..182962 - 933 WP_271073426.1 DMT family transporter -
PAF20_RS17520 (PAF20_17520) 183217..183495 + 279 WP_271073427.1 hypothetical protein -
PAF20_RS17525 (PAF20_17525) 183636..183734 + 99 Protein_165 IS5/IS1182 family transposase -
PAF20_RS17530 (PAF20_17530) 183868..184272 - 405 WP_271073428.1 type II toxin-antitoxin system VapC family toxin Toxin
PAF20_RS17535 (PAF20_17535) 184272..184520 - 249 WP_271073429.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PAF20_RS17540 (PAF20_17540) 184620..186926 - 2307 WP_271073430.1 glycosyltransferase -
PAF20_RS17545 (PAF20_17545) 187315..189312 + 1998 WP_271073431.1 TonB-dependent receptor plug domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..210876 210876


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-48)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14955.02 Da        Isoelectric Point: 6.2277

>T267377 WP_271073428.1 NZ_CP115776:c184272-183868 [Paracoccus albus]
MLILDTNVISALRRPERAPEVAAWLKRQDDNVLYLSVVTLGEIERGIARQEQQDPAFARDLRNWLGRTVQLFGDRLLPFD
AQSARIWGQLSARLGHAGADLLIAATALHHDAVVVTRNVSDFEPTGCRIENPFA

Download         Length: 405 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8951.10 Da        Isoelectric Point: 8.6827

>AT267377 WP_271073429.1 NZ_CP115776:c184520-184272 [Paracoccus albus]
MWSLQDAKNKFSAVVDAALAGEPQEVTRRGKPAVVVLSASEYARILAEAQSNRGSFAKHLLTQPRGEVEAERAEARPRDV
AF

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References