Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RHH
Location 95559..96115 Replicon plasmid p1
Accession NZ_CP115769
Organism Paracoccus sediminicola strain SCSIO 76264

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PAF18_RS16115 Protein ID WP_101754684.1
Coordinates 95559..95867 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PAF18_RS16120 Protein ID WP_232816719.1
Coordinates 95864..96115 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAF18_RS16085 (PAF18_16085) 91094..91657 + 564 WP_090525166.1 SAM-dependent methyltransferase -
PAF18_RS16090 (PAF18_16090) 91654..92760 + 1107 WP_090525164.1 glycosyltransferase family 2 protein -
PAF18_RS16095 (PAF18_16095) 92762..93250 + 489 WP_090525163.1 DUF892 family protein -
PAF18_RS16100 (PAF18_16100) 93461..93703 + 243 Protein_103 ISKra4 family transposase -
PAF18_RS16105 (PAF18_16105) 93700..93849 - 150 WP_176805125.1 hypothetical protein -
PAF18_RS16110 (PAF18_16110) 93997..95337 - 1341 WP_271118180.1 hypothetical protein -
PAF18_RS16115 (PAF18_16115) 95559..95867 - 309 WP_101754684.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PAF18_RS16120 (PAF18_16120) 95864..96115 - 252 WP_232816719.1 hypothetical protein Antitoxin
PAF18_RS16125 (PAF18_16125) 96280..96552 + 273 WP_271114193.1 hypothetical protein -
PAF18_RS16130 (PAF18_16130) 96557..97177 + 621 WP_101754687.1 SOS response-associated peptidase -
PAF18_RS16135 (PAF18_16135) 97826..99019 - 1194 WP_252734076.1 acyl-CoA dehydrogenase -
PAF18_RS16140 (PAF18_16140) 99110..100765 - 1656 WP_271118181.1 electron transfer flavoprotein-ubiquinone oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..146119 146119


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11144.79 Da        Isoelectric Point: 7.0119

>T267374 WP_101754684.1 NZ_CP115769:c95867-95559 [Paracoccus sediminicola]
MKTLLIAEPAGRDLEAIVDYIARENPAAAENVYRQIARTAAKLPEFPALGRPGRFSGTREMNVAGSPYLIVYEVNVEAVT
ILAVFHTSRNLAAALRDRMEGS

Download         Length: 309 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9006.05 Da        Isoelectric Point: 4.6855

>AT267374 WP_232816719.1 NZ_CP115769:c96115-95864 [Paracoccus sediminicola]
MPQRAETEPMTVRTARVSEIDALAAAMDRSRNYVVNQAIDQFLEANAWQMERIAAGVAAAREGNVSSADDVFGAIATKHG
WQA

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References