Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1878183..1878328 | Replicon | chromosome |
| Accession | NZ_CP115714 | ||
| Organism | Klebsiella pneumoniae strain KPN0421 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1878219..1878321 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1878183..1878328 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PF051_RS09175 | 1873313..1875373 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| PF051_RS09180 | 1875377..1876036 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| PF051_RS09185 | 1876115..1876345 | - | 231 | WP_048254886.1 | DNA polymerase III subunit theta | - |
| PF051_RS09190 | 1876458..1876832 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| PF051_RS09195 | 1876836..1877705 | + | 870 | WP_004891049.1 | copper homeostasis membrane protein CopD | - |
| PF051_RS09200 | 1877722..1878060 | + | 339 | WP_016529031.1 | YebY family protein | - |
| - | 1878183..1878328 | - | 146 | - | - | Antitoxin |
| - | 1878219..1878321 | + | 103 | - | - | Toxin |
| PF051_RS09205 | 1878696..1878839 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| PF051_RS09210 | 1878944..1879912 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| PF051_RS09215 | 1880069..1880722 | + | 654 | WP_020802220.1 | protein-serine/threonine phosphatase | - |
| PF051_RS09220 | 1880719..1880910 | - | 192 | WP_002911395.1 | YebW family protein | - |
| PF051_RS09225 | 1881008..1881247 | - | 240 | WP_002911393.1 | YebV family protein | - |
| PF051_RS09230 | 1881363..1882796 | - | 1434 | WP_071081310.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T267345 NZ_CP115714:1878219-1878321 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT267345 NZ_CP115714:c1878328-1878183 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
