Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 3982473..3983128 Replicon chromosome
Accession NZ_CP115713
Organism Rhodopseudomonas palustris strain k7

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OOZ54_RS18595 Protein ID WP_271100442.1
Coordinates 3982473..3982877 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OOZ54_RS18600 Protein ID WP_271102886.1
Coordinates 3982874..3983128 (-) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOZ54_RS18580 (OOZ54_18580) 3977487..3977729 - 243 WP_012496896.1 hypothetical protein -
OOZ54_RS18585 (OOZ54_18585) 3978067..3979290 + 1224 WP_271100440.1 efflux RND transporter periplasmic adaptor subunit -
OOZ54_RS18590 (OOZ54_18590) 3979293..3982430 + 3138 WP_271100441.1 multidrug efflux RND transporter permease subunit -
OOZ54_RS18595 (OOZ54_18595) 3982473..3982877 - 405 WP_271100442.1 PIN domain-containing protein Toxin
OOZ54_RS18600 (OOZ54_18600) 3982874..3983128 - 255 WP_271102886.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
OOZ54_RS18610 (OOZ54_18610) 3983582..3983995 + 414 WP_271100443.1 HI0074 family nucleotidyltransferase substrate-binding subunit -
OOZ54_RS18615 (OOZ54_18615) 3983992..3984324 + 333 WP_271100444.1 nucleotidyltransferase domain-containing protein -
OOZ54_RS18620 (OOZ54_18620) 3984335..3985528 - 1194 WP_271100445.1 CoA transferase -
OOZ54_RS18625 (OOZ54_18625) 3985638..3986849 - 1212 WP_271100446.1 ABC transporter substrate-binding protein -
OOZ54_RS18630 (OOZ54_18630) 3987083..3987697 - 615 WP_271100447.1 class I SAM-dependent methyltransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-114)

Antitoxin

(5-43)


Sequences


Toxin        


Download         Length: 135 a.a.        Molecular weight: 14852.71 Da        Isoelectric Point: 5.4923

>T267340 WP_271100442.1 NZ_CP115713:c3982877-3982473 [Rhodopseudomonas palustris]
VRAFFDTNILVYSTTSDPRQATAAACLEQGGFASVQVLNEFVHVARRKLRHDWPQIEVALEQFHTALDDVLPITLTTHAA
AVVLARDHRVSFYDALIVAAAQEAGCDVLYSEDLQHGRSFGTLRVENPFLEGSR

Download         Length: 405 bp


Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9971.31 Da        Isoelectric Point: 5.2872

>AT267340 WP_271102886.1 NZ_CP115713:c3983128-3982874 [Rhodopseudomonas palustris]
MRVSKWGNSLAVRLPKALVDRLELKEGDELNVVDVVERTLMVEKEDRRKAAVERLSKLRWTLPPDYKFDRDEANERYRDE
SNEP

Download         Length: 255 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References