Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4384664..4385180 Replicon chromosome
Accession NZ_CP115712
Organism Kosakonia pseudosacchari strain RX.G5M8

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PF050_RS20940 Protein ID WP_086872939.1
Coordinates 4384664..4384948 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1G4YUC9
Locus tag PF050_RS20945 Protein ID WP_017459099.1
Coordinates 4384938..4385180 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF050_RS20925 (PF050_20925) 4379757..4381412 + 1656 WP_097401734.1 alpha,alpha-phosphotrehalase -
PF050_RS20930 (PF050_20930) 4381797..4383932 + 2136 WP_086872937.1 anaerobic ribonucleoside-triphosphate reductase -
PF050_RS20935 (PF050_20935) 4384194..4384658 + 465 WP_086872938.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
PF050_RS20940 (PF050_20940) 4384664..4384948 - 285 WP_086872939.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PF050_RS20945 (PF050_20945) 4384938..4385180 - 243 WP_017459099.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PF050_RS20950 (PF050_20950) 4385273..4386193 - 921 WP_086872940.1 AraC family transcriptional regulator -
PF050_RS20955 (PF050_20955) 4386298..4387131 + 834 WP_271064585.1 oxidoreductase -
PF050_RS20960 (PF050_20960) 4387166..4389076 - 1911 WP_271064586.1 PRD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-75)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11066.02 Da        Isoelectric Point: 10.6325

>T267334 WP_086872939.1 NZ_CP115712:c4384948-4384664 [Kosakonia pseudosacchari]
MNYELVFDPRAYKEWKKLGATVKTQFKKKLAEVLVQPRIEKARLHQFPDCYKIKLRTSGYRLVYQVRDNVVTVFVVSIGK
REKAAAYQDASKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9176.65 Da        Isoelectric Point: 4.8409

>AT267334 WP_017459099.1 NZ_CP115712:c4385180-4384938 [Kosakonia pseudosacchari]
MATLNVRLDDKLKEEAWRVLEKLNITPTEAVRLLFQYVAENGRMPIKTVTVSEDESALLEIVRERLANPQKGIKVNLDEL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1G4YUC9

References