Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 4246894..4247458 Replicon chromosome
Accession NZ_CP115712
Organism Kosakonia pseudosacchari strain RX.G5M8

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PF050_RS20280 Protein ID WP_271064515.1
Coordinates 4246894..4247199 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PF050_RS20285 Protein ID WP_086870332.1
Coordinates 4247186..4247458 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF050_RS20265 (PF050_20265) 4243905..4244108 + 204 WP_007373011.1 YbdD/YjiX family protein -
PF050_RS20270 (PF050_20270) 4244119..4245075 + 957 WP_086870338.1 GTPase -
PF050_RS20275 (PF050_20275) 4245119..4246489 - 1371 WP_271064514.1 NAD-dependent succinate-semialdehyde dehydrogenase -
PF050_RS20280 (PF050_20280) 4246894..4247199 - 306 WP_271064515.1 type II toxin-antitoxin system YafQ family toxin Toxin
PF050_RS20285 (PF050_20285) 4247186..4247458 - 273 WP_086870332.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PF050_RS20290 (PF050_20290) 4247555..4248070 + 516 WP_271064516.1 VOC family protein -
PF050_RS20295 (PF050_20295) 4248072..4249175 - 1104 WP_271064517.1 M20 peptidase aminoacylase family protein -
PF050_RS20300 (PF050_20300) 4249193..4249660 - 468 WP_193821734.1 YjiG family protein -
PF050_RS20305 (PF050_20305) 4249653..4250336 - 684 WP_017457805.1 nucleoside recognition domain-containing protein -
PF050_RS20310 (PF050_20310) 4250714..4251610 + 897 WP_271064518.1 LysR substrate-binding domain-containing protein -
PF050_RS20315 (PF050_20315) 4251653..4252423 + 771 WP_271064519.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(11-101)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-85)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11585.22 Da        Isoelectric Point: 8.4472

>T267333 WP_271064515.1 NZ_CP115712:c4247199-4246894 [Kosakonia pseudosacchari]
MGKSKRAPLPYRSDYTKTFIKAWERYNRAGRRDMHETAAVMSLILSGNPLPAQYNDHALTGDMVGFRELHIGGDYLLVYR
VDKDKHLVVFTDIGTHAELFE

Download         Length: 306 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10078.45 Da        Isoelectric Point: 5.8481

>AT267333 WP_086870332.1 NZ_CP115712:c4247458-4247186 [Kosakonia pseudosacchari]
MDSIIRSRINSDLKARAGSVLESCGLNWSTAIRLFAEQIVKTEGIPFEVTRKPTARLRKAMTETEDILAHQNGRFDGIDQ
LMDSLNDGKE

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References