Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) kacAT/DUF1778(antitoxin)
Location 3552572..3553366 Replicon chromosome
Accession NZ_CP115712
Organism Kosakonia pseudosacchari strain RX.G5M8

Toxin (Protein)


Gene name KacT Uniprot ID -
Locus tag PF050_RS17100 Protein ID WP_271064258.1
Coordinates 3552845..3553366 (+) Length 174 a.a.

Antitoxin (Protein)


Gene name KacA Uniprot ID -
Locus tag PF050_RS17095 Protein ID WP_271064257.1
Coordinates 3552572..3552841 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF050_RS17060 (PF050_17060) 3548087..3548701 + 615 WP_086871479.1 methylthioribulose 1-phosphate dehydratase -
PF050_RS17065 (PF050_17065) 3548698..3549387 + 690 WP_271064254.1 acireductone synthase -
PF050_RS17070 (PF050_17070) 3549384..3549926 + 543 WP_097400587.1 acireductone dioxygenase -
PF050_RS17075 (PF050_17075) 3550198..3551517 - 1320 WP_271064255.1 hypothetical protein -
PF050_RS17080 (PF050_17080) 3551634..3551813 - 180 WP_090118831.1 hypothetical protein -
PF050_RS17085 (PF050_17085) 3551941..3552063 + 123 WP_271064256.1 hypothetical protein -
PF050_RS17090 (PF050_17090) 3552053..3552370 + 318 WP_086871467.1 hypothetical protein -
PF050_RS17095 (PF050_17095) 3552572..3552841 + 270 WP_271064257.1 DUF1778 domain-containing protein Antitoxin
PF050_RS17100 (PF050_17100) 3552845..3553366 + 522 WP_271064258.1 GNAT family N-acetyltransferase Toxin
PF050_RS17105 (PF050_17105) 3553388..3553605 - 218 Protein_3353 helix-turn-helix transcriptional regulator -
PF050_RS17110 (PF050_17110) 3553858..3554430 + 573 WP_271064259.1 DUF1349 domain-containing protein -
PF050_RS17115 (PF050_17115) 3554882..3556420 + 1539 WP_086871457.1 methyl-accepting chemotaxis protein -
PF050_RS17120 (PF050_17120) 3556502..3556690 - 189 WP_271064260.1 hypothetical protein -
PF050_RS17125 (PF050_17125) 3556738..3557010 - 273 WP_271064261.1 MafI family immunity protein -
PF050_RS17130 (PF050_17130) 3557007..3557345 - 339 WP_193822030.1 SdpI family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(94-150)

Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 174 a.a.        Molecular weight: 19357.19 Da        Isoelectric Point: 8.9007

>T267331 WP_271064258.1 NZ_CP115712:3552845-3553366 [Kosakonia pseudosacchari]
VDKLTIEMFSGETEYETGGFDCGEVSLNTFLTQHLKRQHDGKILRAYILQTATARPRVFGYYTLSGGSFEKAQLPTKTQQ
KKMPYRTVPCVTLGRLAVDKTRQGNGWGEMLVAHAMKVVYNASLAVGVHGLFVEALTDNAKNFYEKLGFIPLAEGNPHSL
FYPTKSIERLFTE

Download         Length: 522 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10271.74 Da        Isoelectric Point: 8.7342

>AT267331 WP_271064257.1 NZ_CP115712:3552572-3552841 [Kosakonia pseudosacchari]
MPALKKQRIDLRLTDEDKKMIEEAAAMTNQTITQFLVSSASERAAEVIEQHRRLVLSEESWNRVMDAIENPPAPNDKLKR
AAKRLQNRE

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References