Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 926883..927443 Replicon chromosome
Accession NZ_CP115712
Organism Kosakonia pseudosacchari strain RX.G5M8

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag PF050_RS04455 Protein ID WP_086873568.1
Coordinates 926883..927194 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag PF050_RS04460 Protein ID WP_086873569.1
Coordinates 927198..927443 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF050_RS04430 (PF050_04430) 922614..923189 + 576 WP_271069433.1 ABATE domain-containing protein -
PF050_RS04435 (PF050_04435) 923233..923409 + 177 WP_271069434.1 hypothetical protein -
PF050_RS04440 (PF050_04440) 923537..924604 - 1068 WP_271069435.1 SDR family oxidoreductase -
PF050_RS04445 (PF050_04445) 924708..925640 + 933 WP_097401592.1 LysR family transcriptional regulator -
PF050_RS04450 (PF050_04450) 925705..926826 + 1122 WP_271069436.1 cupin domain-containing protein -
PF050_RS04455 (PF050_04455) 926883..927194 - 312 WP_086873568.1 CcdB family protein Toxin
PF050_RS04460 (PF050_04460) 927198..927443 - 246 WP_086873569.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
PF050_RS04465 (PF050_04465) 927568..928284 - 717 WP_086873570.1 nitroreductase family protein -
PF050_RS04470 (PF050_04470) 929047..930375 + 1329 WP_271069437.1 diguanylate cyclase -
PF050_RS04475 (PF050_04475) 930396..931538 - 1143 WP_086873573.1 PLP-dependent aspartate aminotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-102)

Antitoxin

Post-segregation antitoxin CcdA

(11-81)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11747.56 Da        Isoelectric Point: 5.0896

>T267324 WP_086873568.1 NZ_CP115712:c927194-926883 [Kosakonia pseudosacchari]
MQYSVYRNKSNSRDFPFLLDVQSDIIGSMNSRVVIPLCPLADYKDRRRVERLNPVLEIEGKPYLLLTHDLAGVSLAILGE
EVCSMNAQRDVIRNAMDFIFDGI

Download         Length: 312 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9275.35 Da        Isoelectric Point: 7.2061

>AT267324 WP_086873569.1 NZ_CP115712:c927443-927198 [Kosakonia pseudosacchari]
MPATAAKQRNKQNVSVTVERDLLEQARKEGINLSQTLTNALQGELRNLEAERWKRENAAAIADLNEFIAERGHFSDEHRK
F

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References