Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 879604..880267 Replicon chromosome
Accession NZ_CP115712
Organism Kosakonia pseudosacchari strain RX.G5M8

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PF050_RS04245 Protein ID WP_086873527.1
Coordinates 879851..880267 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1G4Y1L0
Locus tag PF050_RS04240 Protein ID WP_017457616.1
Coordinates 879604..879870 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF050_RS04220 (PF050_04220) 875135..876568 - 1434 WP_097400858.1 6-phospho-beta-glucosidase -
PF050_RS04225 (PF050_04225) 876685..877413 - 729 WP_086873857.1 MurR/RpiR family transcriptional regulator -
PF050_RS04230 (PF050_04230) 877653..878312 + 660 WP_086873525.1 hemolysin III family protein -
PF050_RS04235 (PF050_04235) 878374..879357 - 984 WP_086873526.1 tRNA-modifying protein YgfZ -
PF050_RS04240 (PF050_04240) 879604..879870 + 267 WP_017457616.1 FAD assembly factor SdhE Antitoxin
PF050_RS04245 (PF050_04245) 879851..880267 + 417 WP_086873527.1 protein YgfX Toxin
PF050_RS04250 (PF050_04250) 880280..880801 - 522 WP_271069415.1 flavodoxin FldB -
PF050_RS04255 (PF050_04255) 880901..881797 + 897 WP_193821132.1 site-specific tyrosine recombinase XerD -
PF050_RS04260 (PF050_04260) 881822..882535 + 714 WP_271069416.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PF050_RS04265 (PF050_04265) 882541..884274 + 1734 WP_271069417.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16374.29 Da        Isoelectric Point: 11.0079

>T267323 WP_086873527.1 NZ_CP115712:879851-880267 [Kosakonia pseudosacchari]
VVLWQSDLRVSWRAQWISLLLHGLVAAFILFMPWPLSYTPLWLLLLSLVVFDCVRSQRRINACHGEIKLLMDSRLRWQGV
EWDIIGTPWMIRGGMMLRLRRAEDGRRQHLWLAADSMDSQEWRDLRRMITQNPAQGLH

Download         Length: 417 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10521.95 Da        Isoelectric Point: 6.0701

>AT267323 WP_017457616.1 NZ_CP115712:879604-879870 [Kosakonia pseudosacchari]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDHDKQVFVRLLESDDPDLFNWLMNHGKPQDAELQRMVQLIQTRN
RDRGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1G4Y1L0

References