Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 301029..301737 Replicon chromosome
Accession NZ_CP115712
Organism Kosakonia pseudosacchari strain RX.G5M8

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PF050_RS01390 Protein ID WP_271064990.1
Coordinates 301029..301427 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PF050_RS01395 Protein ID WP_086872794.1
Coordinates 301420..301737 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF050_RS01365 (PF050_01365) 296157..297815 + 1659 WP_271064988.1 lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase -
PF050_RS01370 (PF050_01370) 297829..298167 + 339 WP_271064989.1 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE -
PF050_RS01375 (PF050_01375) 298164..298550 + 387 WP_097399896.1 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF -
PF050_RS01380 (PF050_01380) 298554..299603 - 1050 WP_097399897.1 AI-2E family transporter -
PF050_RS01385 (PF050_01385) 299749..300948 + 1200 WP_086872797.1 MFS transporter -
PF050_RS01390 (PF050_01390) 301029..301427 + 399 WP_271064990.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PF050_RS01395 (PF050_01395) 301420..301737 + 318 WP_086872794.1 helix-turn-helix domain-containing protein Antitoxin
PF050_RS01400 (PF050_01400) 301797..302354 - 558 WP_086872792.1 DcrB family lipoprotein -
PF050_RS01405 (PF050_01405) 302427..303092 - 666 WP_086872790.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
PF050_RS01410 (PF050_01410) 303280..303525 + 246 WP_086872859.1 sulfurtransferase TusA -
PF050_RS01415 (PF050_01415) 303522..305738 - 2217 WP_271064991.1 Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase ZntA -
PF050_RS01420 (PF050_01420) 305814..306440 - 627 WP_086872786.1 lysoplasmalogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(4-128)

Antitoxin

Cro/C1-type helix-turn-helix domain

(49-89)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15032.46 Da        Isoelectric Point: 8.9414

>T267321 WP_271064990.1 NZ_CP115712:301029-301427 [Kosakonia pseudosacchari]
MDSMGIYLTREFDQERRRVRVSDKILRKAALAIVAGLPGDKLGKYTYKKRIALPAVSARDGARAIVFFHAGENLFFFDMY
VKSELSKKRGKELEDDEIDAYCAIAKDFIAMPADTLKRLLSSKDLIEVNCYE

Download         Length: 399 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11674.46 Da        Isoelectric Point: 10.6919

>AT267321 WP_086872794.1 NZ_CP115712:301420-301737 [Kosakonia pseudosacchari]
MSDHLKRIQSMAKRYNALGVVQDETVAAIDEAIDARNIPQVRPMTGVQIKQVRARWKMSQAALARTVGMSVESVSKWERN
ESKPNNAALRILNTIEDKGPAVFLG

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References