Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1966638..1966783 Replicon chromosome
Accession NZ_CP115707
Organism Klebsiella pneumoniae strain CPE16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1966674..1966776 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1966638..1966783 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PGD48_RS09695 1961768..1963828 + 2061 WP_004151449.1 oligopeptidase B -
PGD48_RS09700 1963832..1964491 - 660 WP_043906809.1 exodeoxyribonuclease X -
PGD48_RS09705 1964570..1964800 - 231 WP_002911406.1 DNA polymerase III subunit theta -
PGD48_RS09710 1964913..1965287 + 375 WP_004151448.1 CopC domain-containing protein YobA -
PGD48_RS09715 1965291..1966160 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
PGD48_RS09720 1966177..1966515 + 339 WP_002911404.1 YebY family protein -
- 1966638..1966783 - 146 - - Antitoxin
- 1966674..1966776 + 103 - - Toxin
PGD48_RS09725 1967152..1967295 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
PGD48_RS09730 1967400..1968368 - 969 WP_004151446.1 VirK/YbjX family protein -
PGD48_RS09735 1968525..1969178 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
PGD48_RS09740 1969175..1969366 - 192 WP_002911395.1 YebW family protein -
PGD48_RS09745 1969464..1969703 - 240 WP_002911393.1 YebV family protein -
PGD48_RS09750 1969819..1971252 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1893583..1979854 86271


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T267305 NZ_CP115707:1966674-1966776 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT267305 NZ_CP115707:c1966783-1966638 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References