Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2019747..2019892 | Replicon | chromosome |
| Accession | NZ_CP115701 | ||
| Organism | Klebsiella pneumoniae strain 2020CK-00201 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2019783..2019885 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2019747..2019892 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PF326_RS09995 (PF326_09995) | 2014877..2016937 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| PF326_RS10000 (PF326_10000) | 2016941..2017600 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| PF326_RS10005 (PF326_10005) | 2017679..2017909 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| PF326_RS10010 (PF326_10010) | 2018022..2018396 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| PF326_RS10015 (PF326_10015) | 2018400..2019269 | + | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| PF326_RS10020 (PF326_10020) | 2019286..2019624 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2019747..2019892 | - | 146 | - | - | Antitoxin |
| - | 2019783..2019885 | + | 103 | - | - | Toxin |
| PF326_RS10025 (PF326_10025) | 2020260..2020403 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| PF326_RS10030 (PF326_10030) | 2020508..2021476 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| PF326_RS10035 (PF326_10035) | 2021633..2022286 | + | 654 | WP_002911396.1 | protein-serine/threonine phosphatase | - |
| PF326_RS10040 (PF326_10040) | 2022283..2022474 | - | 192 | WP_002911395.1 | YebW family protein | - |
| PF326_RS10045 (PF326_10045) | 2022572..2022811 | - | 240 | WP_002911393.1 | YebV family protein | - |
| PF326_RS10050 (PF326_10050) | 2022927..2024360 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T267293 NZ_CP115701:2019783-2019885 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT267293 NZ_CP115701:c2019892-2019747 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
