Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2726845..2727046 Replicon chromosome
Accession NZ_CP115696
Organism Enterobacter hormaechei strain 2020CK-00202

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2726850..2726953 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2726845..2727046 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF328_RS12935 (PF328_12935) 2722061..2722321 - 261 WP_039270557.1 hypothetical protein -
PF328_RS12940 (PF328_12940) 2722305..2722589 - 285 WP_039270555.1 phage holin family protein -
PF328_RS12945 (PF328_12945) 2722729..2722926 - 198 WP_127850788.1 hypothetical protein -
PF328_RS12950 (PF328_12950) 2722956..2723390 - 435 WP_039270553.1 hypothetical protein -
PF328_RS12960 (PF328_12960) 2724836..2725351 - 516 WP_039270551.1 hypothetical protein -
PF328_RS12965 (PF328_12965) 2725584..2725997 - 414 WP_052685510.1 bacteriophage antitermination protein Q -
PF328_RS12970 (PF328_12970) 2726387..2726761 + 375 Protein_2533 tyrosine-type recombinase/integrase -
- 2726845..2727046 + 202 - - Antitoxin
- 2726850..2726953 - 104 - - Toxin
PF328_RS12975 (PF328_12975) 2727095..2727433 - 339 WP_003859787.1 YebY family protein -
PF328_RS12980 (PF328_12980) 2727450..2728319 - 870 WP_017693249.1 copper homeostasis membrane protein CopD -
PF328_RS12985 (PF328_12985) 2728321..2728692 - 372 WP_023296802.1 CopC domain-containing protein YobA -
PF328_RS12990 (PF328_12990) 2728830..2729060 + 231 WP_003859784.1 DNA polymerase III subunit theta -
PF328_RS12995 (PF328_12995) 2729172..2729822 + 651 WP_015570289.1 carbon-nitrogen hydrolase family protein -
PF328_RS13000 (PF328_13000) 2729847..2730509 + 663 WP_039270549.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2710629..2747791 37162


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T267281 NZ_CP115696:c2726953-2726850 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 202 bp

>AT267281 NZ_CP115696:2726845-2727046 [Enterobacter hormaechei]
CAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGCAAAAGTGGT
CTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References