Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2726849..2727050 Replicon chromosome
Accession NZ_CP115672
Organism Enterobacter hormaechei strain 2020CK-00203

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2726854..2726957 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2726849..2727050 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF324_RS12935 (PF324_12935) 2722065..2722325 - 261 WP_039270557.1 hypothetical protein -
PF324_RS12940 (PF324_12940) 2722309..2722593 - 285 WP_039270555.1 phage holin family protein -
PF324_RS12945 (PF324_12945) 2722733..2722930 - 198 WP_127850788.1 hypothetical protein -
PF324_RS12950 (PF324_12950) 2722960..2723394 - 435 WP_039270553.1 hypothetical protein -
PF324_RS12960 (PF324_12960) 2724840..2725355 - 516 WP_039270551.1 hypothetical protein -
PF324_RS12965 (PF324_12965) 2725588..2726001 - 414 WP_052685510.1 bacteriophage antitermination protein Q -
PF324_RS12970 (PF324_12970) 2726391..2726765 + 375 Protein_2533 tyrosine-type recombinase/integrase -
- 2726849..2727050 + 202 - - Antitoxin
- 2726854..2726957 - 104 - - Toxin
PF324_RS12975 (PF324_12975) 2727099..2727437 - 339 WP_003859787.1 YebY family protein -
PF324_RS12980 (PF324_12980) 2727454..2728323 - 870 WP_017693249.1 copper homeostasis membrane protein CopD -
PF324_RS12985 (PF324_12985) 2728325..2728696 - 372 WP_023296802.1 CopC domain-containing protein YobA -
PF324_RS12990 (PF324_12990) 2728834..2729064 + 231 WP_003859784.1 DNA polymerase III subunit theta -
PF324_RS12995 (PF324_12995) 2729176..2729826 + 651 WP_015570289.1 carbon-nitrogen hydrolase family protein -
PF324_RS13000 (PF324_13000) 2729851..2730513 + 663 WP_039270549.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2710633..2747795 37162


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T267255 NZ_CP115672:c2726957-2726854 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 202 bp

>AT267255 NZ_CP115672:2726849-2727050 [Enterobacter hormaechei]
CAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGCAAAAGTGGT
CTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References