Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yoeB-relE/YoeB-RelB
Location 2837386..2837900 Replicon chromosome
Accession NZ_CP115671
Organism Brevundimonas vesicularis strain PL22-8A

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PFY01_RS14410 Protein ID WP_271041792.1
Coordinates 2837640..2837900 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag PFY01_RS14405 Protein ID WP_271041791.1
Coordinates 2837386..2837643 (+) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PFY01_RS14380 (PFY01_14380) 2832788..2833006 + 219 WP_271041790.1 helix-turn-helix transcriptional regulator -
PFY01_RS14385 (PFY01_14385) 2833204..2833620 + 417 WP_153923116.1 DoxX family protein -
PFY01_RS14390 (PFY01_14390) 2833812..2834294 + 483 WP_039244783.1 MerR family DNA-binding transcriptional regulator -
PFY01_RS14395 (PFY01_14395) 2834298..2836082 + 1785 WP_174085315.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -
PFY01_RS14400 (PFY01_14400) 2836179..2837342 + 1164 WP_055806174.1 acyl-CoA dehydrogenase family protein -
PFY01_RS14405 (PFY01_14405) 2837386..2837643 + 258 WP_271041791.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PFY01_RS14410 (PFY01_14410) 2837640..2837900 + 261 WP_271041792.1 Txe/YoeB family addiction module toxin Toxin
PFY01_RS14415 (PFY01_14415) 2837897..2838616 + 720 WP_271041793.1 16S rRNA (uracil(1498)-N(3))-methyltransferase -
PFY01_RS14420 (PFY01_14420) 2838818..2840179 + 1362 WP_271041794.1 glutamate--cysteine ligase -
PFY01_RS14425 (PFY01_14425) 2840176..2840913 - 738 WP_271041795.1 hypothetical protein -
PFY01_RS14430 (PFY01_14430) 2841026..2842597 + 1572 WP_271041796.1 ATP-binding protein -
PFY01_RS14435 (PFY01_14435) 2842652..2842897 + 246 WP_045809783.1 type II toxin-antitoxin system ParD family antitoxin -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-84)

Antitoxin

(1-73)


Sequences


Toxin        


Download         Length: 87 a.a.        Molecular weight: 10617.13 Da        Isoelectric Point: 9.4792

>T267250 WP_271041792.1 NZ_CP115671:2837640-2837900 [Brevundimonas vesicularis]
MKLTFQTYGWEDYLHWQDHDRKMLRKLNRLIMECQRTPFSGTGKPEPLKGDFAGWWSRRIDREHRLVYRVTDDALLIAQC
RYHYDR

Download         Length: 261 bp


Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9390.54 Da        Isoelectric Point: 4.2815

>AT267250 WP_271041791.1 NZ_CP115671:2837386-2837643 [Brevundimonas vesicularis]
MNAMSVTELRKNLAAAIDRVTADHDYTIITREGGKPAAVLMSLEDFASWQETEYLLRSPANAARLREAIAELDEGGGQVR
ELIEE

Download         Length: 258 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References