Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PanAT/Fic-DUF4065 |
| Location | 2973297..2974346 | Replicon | chromosome |
| Accession | NZ_CP115670 | ||
| Organism | Corynebacterium sp. SCR221107 | ||
Toxin (Protein)
| Gene name | panT | Uniprot ID | - |
| Locus tag | PAB09_RS12930 | Protein ID | WP_271034035.1 |
| Coordinates | 2973867..2974346 (+) | Length | 160 a.a. |
Antitoxin (Protein)
| Gene name | panA | Uniprot ID | - |
| Locus tag | PAB09_RS12925 | Protein ID | WP_271034034.1 |
| Coordinates | 2973297..2973863 (+) | Length | 189 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PAB09_RS12910 (PAB09_12910) | 2969262..2969873 | - | 612 | WP_231494063.1 | DUF4194 domain-containing protein | - |
| PAB09_RS12915 (PAB09_12915) | 2969863..2971320 | - | 1458 | WP_271034033.1 | DUF3375 domain-containing protein | - |
| PAB09_RS12920 (PAB09_12920) | 2972673..2972957 | - | 285 | Protein_2511 | leucine--tRNA ligase | - |
| PAB09_RS12925 (PAB09_12925) | 2973297..2973863 | + | 567 | WP_271034034.1 | Panacea domain-containing protein | Antitoxin |
| PAB09_RS12930 (PAB09_12930) | 2973867..2974346 | + | 480 | WP_271034035.1 | Fic family protein | Toxin |
| PAB09_RS12935 (PAB09_12935) | 2974408..2977272 | - | 2865 | WP_271034036.1 | leucine--tRNA ligase | - |
| PAB09_RS12940 (PAB09_12940) | 2977912..2978145 | + | 234 | WP_271034037.1 | BRO family protein | - |
| PAB09_RS12945 (PAB09_12945) | 2978190..2978603 | + | 414 | WP_271034038.1 | phage antirepressor KilAC domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2973297..2979434 | 6137 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 160 a.a. Molecular weight: 17594.99 Da Isoelectric Point: 6.4769
>T267249 WP_271034035.1 NZ_CP115670:2973867-2974346 [Corynebacterium sp. SCR221107]
VTITNEQEWVQLLTDLALRLNQECGTRQNGASHDEYAGFSYDEGALCSAIAAPFQSVFGAPRYESVYDRAAALMAHIAKA
HAFRDGNKRTALKLSLVYLTMRGIRVVPPSAELGAQLVEKCVLANGNQFEQMVVEISTFLIAWTVPDQIAREHRRNVQG
VTITNEQEWVQLLTDLALRLNQECGTRQNGASHDEYAGFSYDEGALCSAIAAPFQSVFGAPRYESVYDRAAALMAHIAKA
HAFRDGNKRTALKLSLVYLTMRGIRVVPPSAELGAQLVEKCVLANGNQFEQMVVEISTFLIAWTVPDQIAREHRRNVQG
Download Length: 480 bp
Antitoxin
Download Length: 189 a.a. Molecular weight: 20933.34 Da Isoelectric Point: 4.6007
>AT267249 WP_271034034.1 NZ_CP115670:2973297-2973863 [Corynebacterium sp. SCR221107]
MADIRDVGQYIVELRGGTVDKHKLAKLCFFAQGWHLAWTGKPLTTSHFQAWIYGPVPTELGRYSTVAEGSKDVTRIATGD
SSRLSDYERAVVASIVDFYGDMDFAVLTKLSHGRSWEEARQGLPENAPSSENLSVSTMREEFSHLVHDSGELPQAPTFNE
DLDLEAALAASELVENDWMETFHLLATR
MADIRDVGQYIVELRGGTVDKHKLAKLCFFAQGWHLAWTGKPLTTSHFQAWIYGPVPTELGRYSTVAEGSKDVTRIATGD
SSRLSDYERAVVASIVDFYGDMDFAVLTKLSHGRSWEEARQGLPENAPSSENLSVSTMREEFSHLVHDSGELPQAPTFNE
DLDLEAALAASELVENDWMETFHLLATR
Download Length: 567 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|